Prior Abdominal Surgery: A Potential Risk Factor for Colonic Diverticulosis or Diverticulitis

Background & Aims:

Abnormal colonic pressure profiles have been associated with an increased risk of colonic diverticulosis. A surgical history is a known risk factor for abdominal adhesions, and these may lead to increased intraluminal colonic pressure. We assessed whether previous abdominal surgery is associated with colonic diverticulosis or diverticulitis.

Methods:

The investigators analyzed data from a prospective study of patients undergoing colonoscopy for different indications from 2020 through 2021. Patients completed a structured questionnaire concerning previous abdominal surgeries, dietary and lifestyle exposures including smoking and alcohol use, and co-morbidities.

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Key information

Conditions

Diverticulosis, Colonic Abdominal Adhesion Colonic Diseases Digestive System Diseases Diverticular Diseases Diverticulitis Gastroenteritis Gastrointestinal Diseases Intestinal Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Asag Harofeh Medical Center

Be’er Ya‘aqov, 70300, Israel

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

patients > 18 years old who are going through colonoscopy in shamir medical center for any reason

Exclusion criteria

inadequate preparation (Boston Bowel Preparation Quality Scale <6);
previous colonic resection based on history and colonoscopy;
previous colon cancer.

Treatment and study plan

comparison

Other

abdominal surgery as a risk factor for diverticulosis

Primary outcomes

correlation between prior abdominal surgery and the development of diverticulosis

Time frame: in the end of the study (estimated in 1 year)

the investigators are willing to see if prior abdominal surgery raise the patient's risk of developing future diverticulosis. The investigators use questionere to collect data from patients. The final measurements will be calculatrd with spss software

Sponsors and collaborators

Lead sponsor

Assaf-Harofeh Medical Center

Other Gov

Registry information

Important dates

Study start: 2020
Primary completion: 2021
Study completion: 2022
First posted: May 20, 2022
Registry last updated: May 26, 2022

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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Completed