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Completed

NCT Number: NCT06664398

Preventive Effects of Different Volumes of High-Intensity Interval Training on Risk Factors for MS in Overweight Young Women

This study investigates the effects of different volumes of high-intensity interval training on risk factors for metabolic syndrome in overweight young women.

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Key information

Conditions

Metabolic Syndrome Body Weight Glucose Metabolism Disorders Hyperinsulinism Insulin Resistance Metabolic Diseases Nutrition Disorders Nutritional and Metabolic Diseases Overnutrition Overweight Pathological Conditions, Signs and Symptoms Signs and Symptoms

Age range

18 year–30 year

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Primary location

School of Sports Medicine and Rehabilitation, Beijing Sport University

Beijing, China

About this study

The sedentary and inactive female overweight subjects, aged 18 to 30 years, were randomly divided into three groups: high volume high-intensity interval training group (4HIIT group), low volume high-intensity interval training group (1HIIT group) and control group (CON group). Human morphological measures, blood pressure, insulin resistance, blood analysis, and cardiorespiratory fitness were measured at baseline and after exercise intervention.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Women aged 18-30 years;
  • BMI≥24kg/m2, indicating overweight and high risk of metabolic syndrome;
  • Maintaining a stable body weight for the three months prior to the study.

Exclusion criteria

  • Regular participation in physical exercise (≥3 times/week, exercise time≥30min/time);
  • Any respiratory, musculoskeletal, or cardiovascular diseases;
  • Medical or other contraindications for exercise;
  • Taking medications that affect metabolism;
  • Smoking and/or drinking habits.

Treatment and study plan

one HIIT

Behavioral

one HIIT high intensity interval training

four HIIT

Behavioral

four HIIT high intensity interval training

Primary outcomes

  1. Weight

    Time frame: 8 weeks

    Changes in Weight before and after intervention.

  2. Body Mass Index (BMI)

    Time frame: 8 weeks

    Changes in BMI before and after intervention.

  3. body fat percentage

    Time frame: 8 weeks

    Changes in body fat percentage before and after intervention.

  4. waist circumference (WC)

    Time frame: 8 weeks

    Changes in WC before and after intervention.

  5. Systolic blood pressure (SBP)

    Time frame: 8 weeks

    Changes in SBP before and after intervention.

  6. Diastolic blood pressure (DBP)

    Time frame: 8 weeks

    Changes in DBP before and after intervention.

  7. Fasting plasma glucose (FPG)

    Time frame: 8 weeks

    Changes in FPG before and after intervention.

  8. Triglyceride (TG)

    Time frame: 8 weeks

    Changes in TG before and after intervention.

  9. High-density lipoprotein cholesterol (HDL-C)

    Time frame: 8 weeks

    Changes in HDL-C before and after intervention.

Secondary outcomes

  1. Non high-density lipoprotein cholesterol (Non HDL-C)

    Time frame: 8 weeks

    Changes in HDL-C before and after intervention.

  2. Insulin

    Time frame: 8 weeks

    Changes in insulin before and after intervention.

  3. Homeostatic model assessment for insulin resistance (HOMA-IR)

    Time frame: 8 weeks

    12、Homeostatic model assessment for insulin resistance (HOMA-IR) Changes in HOMA-IR before and after intervention.

  4. Triglyceride-glucose (TyG) index

    Time frame: 8 weeks

    Changes in TyG index before and after intervention.

  5. Triglyceride-to-high density lipoprotein cholesterol ratio (TG/HDL-C ratio)

    Time frame: 8 weeks

    Changes in TG/HDL-C ratio before and after intervention.

  6. Visceral fat area (VFA)

    Time frame: 8 weeks

    Changes in VFA before and after intervention.

Sponsors and collaborators

Lead sponsor

Beijing Sport University

Other

Registry information

Official study title

Preventive Effects of Different Volumes of High-Intensity Interval Training on Risk Factors for Metabolic Syndrome in Overweight Young Women

Important dates

Study start
2021
Primary completion
2021
Study completion
2021
First posted
Oct 29, 2024
Registry last updated
Oct 29, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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