Skip to main content
OpenTrials
Not Yet Recruiting

NCT Number: NCT06515561

Prevalence of Teeth Discoloration , Associated Risk Factors and the Most Common Shade Among Group of Egyptian Population

"The aim of this study is to assess the prevalence of tooth discoloration and explore its associated risk factors, including local cultural practices or environmental conditions, among a group of adults aged 20 to 45 years in an Egyptian population sample. Moreover, we aim to identify the most common dental shades in the same sample."

Not Yet Recruiting

Trial opening soon.

Get Notified

Key information

Age range

20 year–45 year

Sex eligibility

All sexes

Study type

Observational

About this study

Discoloration of teeth is a frequent dental finding and it is often esthetically displeasing and psychologically traumatizing to the patient (Manuel et al., 2010). Changes in the three distinct layers of the tooth; enamel, dentin and cementum are known to cause modification in the appearance of the teeth leading to a change in its light transmission and reflection properties (Watts et al., 2001). Generally, tooth discoloration is said to have occurred when there is a deviation in tooth color. Suresh and Gopi in 2010 noted that the normal color of primary teeth is bluish white, whereas the color of permanent teeth is grayish white or yellowish white. The teeth of adults usually appear more yellow or grayish yellow than those of younger persons because as one ages, the enamel becomes thinner from physiological wear, while the dentin becomes thicker from the deposition of secondary dentin. There are two types of tooth discoloration, extrinsic and intrinsic, while the extrinsic type is apparent on the outer surface of the teeth, the intrinsic type stains are coming from inside of the teeth. The main cause of intrinsic tooth discoloration is the decomposition of pulp tissue, which is the first indication of pulp death (Suresh & Gopi., 2010). Other causes of intrinsic tooth discoloration are enamel opacities, dental caries, tetracycline, minocycline and doxycycline staining, and enamel hypoplasia (Koleoso et al., 2004). These medications can leave a characteristic bright-yellow band that fluoresces under ultraviolet light (tetracycline) or a green-gray or blue-gray intrinsic staining (minocycline). Also, Fluoride can cause enamel discoloration through hypomineralization when too much of it is ingested during the early maturation stage of enamel formation. In addition, dental materials used for dental restorations like amalgam restorations, can generate corrosion products such as silver sulfide which can leave a gray-black color on the teeth.

On the other hand, extrinsic dental discoloration might be due to tea, coffee, tobacco smoking/chewing, betel nut chewing, drugs (e.g., chlorhexidine mouth rinse), iron salts, heavy metals (e.g., silver nitrate and lead), essential oils, amoxicillin-clavulinic acid, ciprofloxacin, linezolide, and glibenclamide (Kumar et al., 2012). Enamel defects, salivary dysfunction, and poor oral hygiene could be predisposing factors to extrinsic discoloration. Small pits and defects on the outer surface of the enamel can lead to an accumulation of food particles and stains from beverages, tobacco, and other topical agents on its surface causing the discoloration. Salivary dysfunction such as, decreased salivation can lead to difficulties in removing food debris from the tooth surface and can thus contribute to the staining of teeth. Conditions that are associated with a reduction in the salivation are salivary gland obstruction and infection, Sjögren syndrome, head and neck radiation therapy for cancer, chemotherapy, and multiple medications (e.g., anticholinergics, antihypertensive, antipsychotics and antihistamines). All of these can cause teeth discoloration (Patel et al., 2013).

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age 20-45 years.
  • Males or females.
  • Egyptians.
  • Presence of at least 20 teeth in function.
  • Patient compliance.

Exclusion criteria

  • Psychologically unstable or mentally retarded participants
  • Participants with severe periodontal diseases.
  • Participants in need for emergency intervention

Treatment and study plan

Primary outcomes

  1. prevalence and severity of discoloration

    Time frame: 3 months

    assessment of the prevalence and severity of dental discoloration among adults in the study area.

Secondary outcomes

  1. risk factors and their association with discoloration

    Time frame: 3 months

    Identification of risk factors and their association with discoloration in the study population and knowing the most common teeth shade among the same group of population.

  2. Most common teeth shade

    Time frame: 3 months

    determination of most common teeth shade usingVita classical shade guide

Study contacts

Contact information is provided by the study sponsor or research team.

reham nabil, ph degree

CONTACT

[email protected]

00201020249628

sara saber, master

CONTACT

[email protected]

00201152766226

Sponsors and collaborators

Lead sponsor

Cairo University

Other

Registry information

Official study title

Prevalence of Teeth Discoloration and Associated Risk Factors and Determination of the Most Common Shade Among Group of Egyptian Population: Educational Hospital Based Cross Sectional Study

Important dates

Study start
2024
Primary completion
2025
Study completion
2025
First posted
Jul 23, 2024
Registry last updated
Jul 24, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.