Bleaching Effect of Solo and Combined Kiwi Extract and Ozone and Their Impact on Enamel

ozone therapy has been extensively used in dentistry to manage wounds healing, dental caries, oral lichen planus, gingivitis and periodontitis, halitosis, osteonecrosis of the jaw, post-surgical pain, plaque and biofilms, root canal treatment, dentin hypersensitivity, tempro-mandibular joint disorders and teeth whitening, And based on the above, in this study kiwi extract and ozone gas will be used individually and combined to evaluate the resultant effects on bleaching, enamel microhardness and micromorphology.

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Key information

Conditions

Discoloration, Tooth Stomatognathic Diseases Tooth Discoloration Tooth Diseases

Age range

18 year–35 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

A total of the 40 participants aged between (18-35 years) with no gender prediction.
The participation will be entirely voluntary, and a signed statement of informed consent will be obtained prior to the start of the study.
Systemically healthy subject based on medical and drug histories, a subject requiring scaling and polishing with moderate calculus with at least two non-adjacent hypersensitive teeth with Schiff scale scores >1 with air blast stimulus.
Access to sound maxillary anterior teeth.
Vitapan classical shades should be A3 or darker and lighter shades are not included.

Exclusion criteria

Participants with poor oral hygiene.
Participants with missing anterior teeth.
Participants with unrealistic expectations.
Participants with dental caries, those undergoing orthodontic treatment.
Participants with a history of periodontal treatment, pregnant or lactating women and individuals with a history of asthma.
Those who are allergic to kiwi or ozone skin therapy were excluded from the study.
Smokers are excluded from the present study.

Treatment and study plan

Bleaching

Device

Bleaching

Primary outcomes

Color change assessment

Time frame: 24 Hours

all participants will be requested to return after 24 hours to permit rehydration of tooth surfaces before shade assessment Tooth Shades will then record using colorimeter. The color change (ΔE) will be calculated using the formula: ΔE= {(ΔL) 2+ (Δa) 2+ (Δb)
Color change assessment

Time frame: one month

all participants will be requested to return after one month for tooth shades recording using colorimeter. The color change (ΔE) will be calculated using the formula: ΔE= {(ΔL) 2+ (Δa) 2+ (Δb) at one month
Color change assessment

Time frame: three month

all participants will be requested to return after one month for tooth shades recording using colorimeter. The color change (ΔE) will be calculated using the formula: ΔE= {(ΔL) 2+ (Δa) 2+ (Δb) at three months
Color change assessment

Time frame: six months

all participants will be requested to return after one month for tooth shades recording using colorimeter. The color change (ΔE) will be calculated using the formula: ΔE= {(ΔL) 2+ (Δa) 2+ (Δb) at six months

Sponsors and collaborators

Lead sponsor

Al-Azhar University

Other

Registry information

Important dates

Study start: 2024
Primary completion: 2025
Study completion: 2026
First posted: Sep 3, 2024
Registry last updated: Sep 3, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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