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OpenTrials
Completed

NCT Number: NCT01993914

Prevalence of MTHFR Polymorphisms in Venous Disease

The etiologies of varicose veins and the progression to more serious forms of chronic venous disease and identification of appropriate diagnostic tests to better aid patient management by identifying individuals who may benefit from more aggressive treatment and/ or prophylactic measures.

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Key information

Conditions

Varicose Veins Cardiovascular Diseases Embolism and Thrombosis MTHFR Thrombosis Vascular Diseases Venous Disease

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

The Elite Laser Vein Center

Los Angeles, California, 90025, United States

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age 18 or over
  • No venous disease (N=30); or C2-C3 venous disease (N=30); or C4-C6 venous disease (N=30)

Exclusion criteria

  • Pregnancy
  • Cancer
  • Chronic obstructive pulmonary disease (COPD)
  • Any systemic inflammatory disease
  • Any of the following within the previous 30 days:
  • Trauma
  • Any surgery
  • Periods of prolonged inactivity

Treatment and study plan

Primary outcomes

  1. Prevalence of MTHFR mutation between patients

    Time frame: Baseline

    Determine whether the prevalence of the MTHFR mutation differs between patient with varicose veins compared to controls and with or without superficial vein thrombosis.

Sponsors and collaborators

Lead sponsor

Health Diagnostic Laboratory, Inc.

Industry

Registry information

Official study title

Prevalence of MTHFR Polymorphisms in Venous Disease With or Without Concomitant Thrombosis

Acronym: MTHFR

Important dates

Study start
2011
Primary completion
2014
Study completion
2014
First posted
Nov 25, 2013
Registry last updated
Nov 17, 2014

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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