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NCT Number: NCT05779332

Prevalence, Etiology and Effects on Oral Health and Life Quality of Molar Incisor Hypomineralization

Molar incisor hypomineralization (MIH) can lead to many clinical conditions and affect oral health-related quality of life (OHRQoL).

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Key information

Conditions

Molar Incisor Hypomineralization Child, Only Congenital Abnormalities Congenital, Hereditary, and Neonatal Diseases and Abnormalities Dental Caries Dental Deposits Dental Diseases Dental Enamel Hypomineralization Dental Plaque Developmental Defects of Enamel Hematologic Diseases Hemic and Lymphatic Diseases Immune System Diseases Immunoproliferative Disorders Leukemia Leukemia, Lymphoid Lymphatic Diseases Lymphoproliferative Disorders Molar Hypomineralization Neoplasms Neoplasms by Histologic Type Oral Health Pediatric ALL Precursor Cell Lymphoblastic Leukemia-Lymphoma Stomatognathic Diseases Stomatognathic System Abnormalities Tooth Abnormalities Tooth Demineralization Tooth Diseases

Age range

9 year–9 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Sema Aydinoğlu

Rize, Turkey (Türkiye)

About this study

Molar incisor hypomineralization (MIH) can lead to many clinical conditions and affect oral health-related quality of life (OHRQoL). The aim of this study was to determine the prevalence, etiology and impacts of MIH on oral health status and OHRQoL.

Six hundred and fifty-five parents and their children aged 9 years were included in the study. After parents completed the questionnaire about the etiology of MIH, children's OHRQoL was measured by the Child Perceptions Questionnaire (CPQ8-10). Children were evaluated for presence and severity of MIH, dental caries experience and oral hygiene status. Qualitative data were analyzed with the Pearson chi-square and Fisher's exact tests. For the quantitative data, if the normal distribution was not satisfied, Kruskal Wallis/Mann-Whitney U tests were used. Also, Binominal logistic regression analysis was performed and p<0.05 was statistical significant.

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Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Being 9-year-old,
  • Mentally and physically capable of completing the questionnaire,
  • Presence of fully erupted 4 permanent molars and 8 permanent incisors.

Exclusion criteria

  • Children were receiving orthodontic treatment during the examination,
  • Children had enamel hypoplasia or developmental defects,
  • Children had amelogenesis imperfecta or dental fluorosis.

Treatment and study plan

survey application

Other

Children's OHRQoL was measured by the Child Perceptions Questionnaire (CPQ8-10). Oral examination of children were conducted for presence and severity of MIH, dental caries experience and oral hygiene status.

Other names: oral examination

Primary outcomes

  1. To determine the prevalence and etiology of MIH.

    Time frame: up to four months

    A questionnaire was applied to the parents about the etiological factors and the prevalence of MIH was determined by oral examination.

  2. To evaluate the impacts of MIH on oral health status.

    Time frame: up to six months

    Oral health was evaluated by recording dmft (decayed, missing and filled teeth) and plaque index values.

  3. To evaluate the impacts of MIH on OHRQoL.

    Time frame: up to six months

    The impact of MIH on quality of life (OHRQoL) was measured with the Child Perception Questionnaire (CPQ8-10).

Sponsors and collaborators

Lead sponsor

Recep Tayyip Erdogan University Training and Research Hospital

Other

Registry information

Official study title

Prevalence, Etiology and Effects on Oral Health and Life Quality of Molar Incisor Hypomineralization: A Comprehensive Study

Important dates

Study start
2020
Primary completion
2020
Study completion
2020
First posted
Mar 22, 2023
Registry last updated
Mar 22, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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