Federal University of Minas Gerais
Belo Horizonte, Minas Gerais, Brazil
NCT Number: NCT03001102
Clinical trial for prevention, randomized, controlled, blinded, parallel, with three arms which purpose is verify the effects of nursing intervention preoperative bathing with 4% chlorhexidine gluconate, 10% Povidone iodine (PVPI) and soap without antiseptic, for the prevention of surgical site infection (SSI) in patients undergoing hip arthroplasty.
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Notify Me18 year–100 year
All sexes
Interventional
Not applicable
Belo Horizonte, Minas Gerais, Brazil
Despite the recommendation in several guidelines of preoperative bathing with 4% chlorhexidine gluconate as a measure for the prevention of SSI, there is no evidence in the literature that support this practice. The objective of this study is to evaluate the effect of nursing intervention: preoperative bath using 4% chlorhexidine gluconate solutions, 10% povidone iodine degermante or soap without antiseptic for the prevention of SSI in patients undergoing elective hip arthroplasty surgery. The specific objectives are to compare the incidence of SSI in the three interventions, to assess the most effective intervention for the prevention of surgical infection and to estimate the frequency of allergic reactions caused by the use of the solutions. Two intervention groups (4% Chlorhexidine gluconate and PVPI10%) and a control group (without antiseptic soap) composed of 52 patients undergoing hip arthroplasty in each group will be randomized to perform the baths in the period from may 2015 to june 2017. Before the intervention, nasal swabs will be collected of patients to investigate colonization by Staphylococcus aureus.
The expected result is lower ISC rate with the proposed measures.
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Cationic biguanide - antimicrobial action rubbing in the skin.
Other names: HiBiScrub, 4% Chlorhexidine degermante
Polymer soluble in water of iodine with polyvinylpyrrolidone (PVP) - antimicrobial action rubbing in the skin.
Other names: Betadine, 10% Povidone iodine degermante
Liquid soap with glycerin, neutral pH. Skin cleansing
Other names: Non-medicated soap, Soap
Time frame: During the first 90 days after surgery
The infections that develop after the surgical procedure
Time frame: In the first hours after procedure
Adverse reaction to a given product
Federal University of Minas Gerais
Other
Preoperative Bath in Patients Submitted to Hip Arthroplasty: Randomized Clinical Trial
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