Predictors of Physical Activity in Adult Patients With Hemophilic Arthropathy

Physical activity levels will be assessed using the International Physical Activity Questionnaire (IPAQ). This tool assesses physical activity levels in adults aged 18 to 65. It consists of seven questions that ask about the frequency, duration, and intensity of physical activity performed in the last week. It also assesses the time spent walking and sitting. The results are classified into three categories: low, moderate, and high activity. The unit of measurement is metabolic equivalent task (METS), where a higher number of METS indicates greater physical activity.

Fear of movement will be measured using the Tampa Kinesiophobia Scale (TSK). This self-reported questionnaire consists of 17 items, using a 4-point Likert scale. It comprises two subscales: avoidance of physical exertion due to fear of injury or pain, and belief that significant underlying medical problems exist. The total score ranges from 17 to 68 points, with a score of 37 or more indicating a high level of kinesiophobia

The degree of functional independence of patients will be measured using the Functional Independence Scale for Hemophilia (FISH). This tool measures eight activities of daily living: eating, personal hygiene, dressing, transferring from a chair, squatting, walking, climbing stairs, and running. Each activity is rated according to the level of assistance required, using a scale from 1 to 4. The total score can reach a maximum of 32 points, with a higher score indicating greater functional independence.

Pain intensity will be measured using the Visual Analog Scale (VAS). This is a simple and effective tool for measuring pain intensity. It consists of a horizontal line, usually 10 cm long, with one end representing "no pain" and the other "maximum pain imaginable."

The sociodemographic variable age will be measured in months completed from the date of birth

The sociodemographic variable marital status will be measured as a qualitative variable (single/married/divorced/widowed).

The sociodemographic variable educational level will be measured as a qualitative variable (primary education/secondary education/university education/vocational training).

The sociodemographic variable employment status will be measured as a qualitative variable (self-employed/employed by others/civil servant/unemployed/unable to work/retired).

The clinical variable hemophilia type will be measured as a dichotomous variable (hemophilia A/hemophilia B).

The clinical variable drug treatment will be measured as a dichotomous variable (on-demand treatment/prophylactic treatment).

The clinical variable development of antibodies prior to FVIII/FIX concentrates (inhibitors) will be measured as a dichotomous variable (yes/no).

The anthropometric variable weight will be measured as a quantitative variable (measured in kg).

The anthropometric variable height will be measured as a quantitative variable (measured in cm).