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Completed

NCT Number: NCT06170749

Prediction Model for Anemia After Bariatric Surgery

To develop and validate a prediction model for estimating the short and long-term risk of anemia after bariatric surgery.

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Key information

Conditions

Anemia Bariatric Surgery Hematologic Diseases Hemic and Lymphatic Diseases

Age range

16 year–70 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Yuntao Nie

Beijing, 100029, China

About this study

This study aims to develop and validate a prediction model for estimating the probability of anemia for patients with obesity one, three, and five years after sleeve gastrectomy and Roux-en-Y gastric bypass, using preoperative clinical and laboratory data.

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • aged between 16-70 years;
  • body mass index (BMI) ≥ 27.5 kg/m2;
  • complete preoperative and follow-up data.

Exclusion criteria

  • vegetarian;
  • other bariatric procedures;
  • renal failure at baseline;
  • postoperative bleeding (it was defined as a drop in hemoglobin levels > 3 g/dL or a confirmed blood loss requiring treatment after surgery);
  • incomplete preoperative and follow-up data.

Treatment and study plan

Primary outcomes

  1. AUCs of the prediction model at 1, 3, 5 years

    Time frame: 5 years

    This metric shows the discrimination ability of the prediction model.

Secondary outcomes

  1. Brier score

    Time frame: 5 years

    This metric shows the calibration of the model. The Brier score (on a scale ranging from 0 to 1), which calculates the difference between the estimated and observed risk for malignancy with values closer to 0 indicating better calibration, was used to evaluate model calibration.

Other outcomes

  1. AUCs of the prediction model in different subgroups

    Time frame: 5 years

    AUCs of the prediction model in different subgroups, including age (≤ 40 years/>40 years), sex, BMI (≤37.5kg/m2/>37.5kg/m2), smoking history, alcohol consumption, hypertension, and T2DM history.

Sponsors and collaborators

Lead sponsor

China-Japan Friendship Hospital

Other

Collaborators

  • Jining First People's Hospital
  • The Second Hospital of Shandong University
  • The Third Xiangya Hospital of Central South University

Registry information

Important dates

Study start
2017
Primary completion
2024
Study completion
2025
First posted
Dec 14, 2023
Registry last updated
Jul 8, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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