Neonatal Intensive Care Unit UZLeuven
Leuven, Vlaams Brabant, 3000, Belgium
NCT Number: NCT01679275
Congenital heart disease with need for early surgery in newborns is associated with an increased incidence in global impairment in development. The causes of these late adverse neurologic outcomes are multifactoral and include both fixed (or patient-specific factors) and modifiable factors. They relate to both the mechanism of central nervous system injury associated with congenital heart disease and its treatment. Measuring cerebral oxygenation is a promising non-invasive way of cerebral monitoring in a neonatal intensive care unit. The importance of cerebral monitoring in neonates with congenital heart problems at risk of developing neurological complications is increasingly recognized. In this way the most vulnerable moments for the newborn brain can be detected and ,if possible, lead to change in (timing of) treatment.
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All sexes
Observational
Leuven, Vlaams Brabant, 3000, Belgium
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Time frame: 24 months
Neurodevelopmental assessment at 24 months using Bayley scales of infant development II
Time frame: first 3 days of life
Cerebral oxygen saturation and autoregulatory capacity
Time frame: time frame of 1 admission
short term outcome defined as cerebral ultrasound abnormalities at admission and discharge, ICU stay, hospital stay and mortality before discharge
Universitaire Ziekenhuizen KU Leuven
Other
Longitudinal Pre-operative Measurements of Cerebral Oxygenation Using Near Infrared Spectroscopy in Neonates With Congenital Heart Disease.
Acronym: CHD-NIRS
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