Allama Iqbal Teaching Hospital
Dera Ghazi Khan, Punjab Province, 32200, Pakistan
NCT Number: NCT07121764
This study is being done to find out which medicine combination provides better pain relief after surgery in children. Children who are having surgery below the belly button (called infra-umbilical surgery) will receive general anesthesia and a type of pain-blocking injection called a caudal block. This block helps reduce pain after surgery.
The study will compare two types of caudal injections:
One group will receive Bupivacaine alone, a commonly used local anesthetic.
The other group will receive Bupivacaine combined with Dexmedetomidine, a medicine that might help the pain relief last longer.
The main question the researchers want to answer is:
Does adding Dexmedetomidine to Bupivacaine increase the duration of pain relief after surgery in children?
Researchers will also look at:
How long it takes before the child needs the first dose of pain medicine after surgery
How much pain medicine is used in the first 24 hours
How long any movement problems (motor block) last
Whether there are any side effects
Each child will be randomly assigned (like flipping a coin) to one of the two groups. The caudal block will be done after the surgery is completed, while the child is still under anesthesia. The nurse assessing the child's pain will not know which medicine the child received.
Children will be monitored for pain using a standard scoring system (FLACC scale) every few hours after surgery. If the pain score is high (7 or more), the child will receive intravenous paracetamol. Researchers will record how long the pain relief lasts, when the first pain medicine is needed, and the total amount of pain medicine used in the first 24 hours.
The study aims to help doctors choose the most effective and safe method to reduce post-surgery pain in children.
Looking for future studies?
Notify Me1 year–12 year
All sexes
Interventional
Phase 4
Dera Ghazi Khan, Punjab Province, 32200, Pakistan
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
1 ml/kg of 0.25% Bupivacaine will be used for caudal block.
1 ml/kg of 0.25% Bupivacaine PLUS 1 μg/kg Dexmedetomidine in 1 ml Normal Saline will be used for caudal block.
Time frame: From surgery to 24-hours post operatively
Duration of post-operative pain free time (hours): time from surgery to FLACC score ≥7 needing rescue analgesia
Time frame: From surgery to 24-hours post operatively
Total amount (milligrams) of paracetamol consumed
Allama Iqbal Teaching Hospital
Other Gov
Comparison of Post-Operative Analgesia With Bupivacaine Alone Versus Bupivacaine and Dexmedetomidine, in Caudal Block for Infra-Umbilical Surgeries in Children
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
Published trials that share one or more normalized conditions with this study.
NCT06862167
Desarda's Technique, Hernia
Minya, Minya Governorate, Egypt
View Trial DetailsNCT06397014
Function and Appearance, Hernia Repair
Yangzhou, Jiangsu, China
View Trial DetailsNCT07591233
Appendectomy, Laparoscopic, Hernia Repair
Beijing, Beijing Municipality, China
View Trial DetailsNCT07615335
Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities
Kafr ash Shaykh, Egypt
View Trial Details