Emory University Eye Center
Atlanta, Georgia, 30322, United States
NCT Number: NCT01995045
The aim of this study is to evaluate if patients receiving a steroid (triamcinolone acetonide) combined with local anesthesia and antibiotic following retina surgery have better postoperative pain control those receiving local anesthesia and antibiotic alone.
Looking for future studies?
Notify Me18 year–89 year
All sexes
Interventional
Phase 4
Atlanta, Georgia, 30322, United States
Currently, patients undergoing vitreoretinal surgery at the Emory Eye Center and Emory University Hospital receive a injection of local anesthesia behind the eye (retrobulbar) at the start of surgery to minimize discomfort felt during the surgery. At the end of surgery all patients receive a periocular antibiotic and steroid injection. Some patients also receive a retrobulbar injection of local anesthesia (bupivicaine) at the conclusion of surgery in order to decrease postoperative pain and discomfort.
It has been our observation that when the local anesthesia is combined with a steroid (triamcinolone acetonide) in a retrobulbar injection at the conclusion of surgery, patients tend to be pain free for longer intervals then when local anesthesia is used alone. The objective of this study is to evaluate if patients receiving triamcinolone acetonide combined with local anesthesia and antibiotic compared to those receiving local anesthesia and antibiotic alone do better with postoperative pain control.
All eligible patients undergoing vitreoretinal surgery at the Emory Eye Center and Emory University Hospital will be offered enrollment. About 60 patients will be invited to participate in this study. Patients will undergo standard of care surgery. At the conclusion of surgery, patients will receive a retrobulbar antibiotic and anesthetic as standard of care. Half of the patients will receive this mixture plus steroid and the other half will receive this mixture plus saline. On postoperative day 1, patients will be given a questionnaire to assess pain. Pain levels in the two groups will be compared.
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Retrobulbar anesthesia
Other names: Kenalog, Triamcinolone Acetonide
Retrobulbar anesthesia
Other names: Marcaine
Time frame: Post-Operative Day 1 (Up to 24 hours)
The mean pain score assessed by the Visual Analog Pain Scale ranging from 0-10; 10 being the worst possible pain.
Time frame: Post Surgery (Up to 24 hours)
The mean acetaminophen use post surgery in milligrams(mg).
Time frame: Post Surgery (Up to 24 hours)
The mean hydrocodone use post surgery in milligrams(mg).
Time frame: Post Surgery (Up to 24 hours)
The mean oxycodone use post surgery in milligrams(mg).
Emory University
Other
The Effects of Triamcinolone Acetonide With Retrobulbar Anesthesia on Postoperative Pain Control Following Vitreoretinal Surgery
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
Published trials that share one or more normalized conditions with this study.
NCT04891991
Eye Diseases, Proliferative Vitreoretinopathy
Cairo, Egypt
View Trial DetailsNCT06166914
Eye Diseases, Proliferative Vitreoretinopathy
Alexandria, Egypt
View Trial DetailsNCT02192970
Eye Diseases, Proliferative Vitreoretinopathy
Madison, Wisconsin, United States
View Trial DetailsNCT01255293
Cardiovascular Diseases, Diabetes Complications
Philadelphia, Pennsylvania, United States
View Trial Details