Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Patients aged between 12 and 60 years.
Diagnosed with Type 1 or Type 2 Diabetes Mellitus.
In need of root canal treatment on a single-rooted tooth.
A clinical diagnosis of either irreversible pulpitis or necrotic pulp in the indicated tooth.
Willingness and ability to understand and provide written informed consent (and assent with parental consent for minors).
-
Exclusion criteria
Known history of allergy to local anesthetics.
Presence of large periapical radiolucent lesions (typically defined as >5mm in diameter).
Current use of long-term analgesic or anti-inflammatory medication (which could alter pain perception).
Teeth with complex root canal anatomy (e.g., calcified canals, C-shaped canals) that would complicate standard treatment.