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NCT Number: NCT07694180

Postoperative Outcomes of Regional Blocks in Cervical Disc Surgery

The aim of this study is to evaluate the postoperative analgesic efficacy of the Serratus Posterior Superior Intercostal Plane Block (SPSIP block) in patients undergoing Anterior Cervical Discectomy and Fusion (ACDF) surgery and to compare the outcomes with those of patients who do not receive regional anesthesia.

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Key information

Conditions

Acute Pain Neurologic Manifestations Pain Pathological Conditions, Signs and Symptoms Servical Disc Herniation Signs and Symptoms

Age range

18 year–70 year

Sex eligibility

All sexes

Study type

Observational

About this study

Cervical disc disorders may lead to various signs and symptoms, including neck pain, radicular pain in the upper extremities, sensory disturbances, motor weakness, and functional impairment. Anterior cervical discectomy and fusion (ACDF) is a widely accepted surgical procedure for the treatment of cervical disc herniation and other degenerative cervical spine disorders. However, postoperative pain remains a significant concern and may adversely affect recovery and patient comfort.

A multimodal analgesic approach is commonly preferred for postoperative pain management following cervical spine surgery. The incorporation of regional anesthesia techniques may reduce opioid consumption and opioid-related adverse effects while facilitating earlier mobilization, shorter hospital stay, and improved patient satisfaction.

In patients undergoing ACDF surgery, the Serratus Posterior Superior Intercostal Plane Block (SPSIPB) has emerged as a promising regional anesthesia technique for postoperative pain control. This study aims to evaluate the postoperative analgesic efficacy of SPSIPB and compare postoperative outcomes between patients receiving SPSIPB and those managed without regional anesthesia.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients aged between 18 and 70 years.
  • American Society of Anesthesiologists (ASA) physical status I, II, or III.
  • Patients scheduled for elective anterior cervical discectomy and fusion (ACDF) surgery under general anesthesia.
  • Patients who provide written informed consent and agree to participate in the study.

Exclusion criteria

  • Patients with a history of bleeding diathesis or those receiving anticoagulant therapy.
  • Patients with a known allergy or hypersensitivity to local anesthetics or opioid medications.
  • Patients with infection at the planned block site.
  • Patients with a history of previous cervical spine surgery.
  • Patients with a history of gabapentinoid or corticosteroid use within the last 3 weeks.

Treatment and study plan

Primary outcomes

  1. Opioid consumption

    Time frame: 24 hours

  2. 1. Opioid consumption

    Time frame: 24 hours

    In the postoperative period, patients will be given opioids according to their pain density with a patient-controlled device, and the daily Morphine consumption in Patient Controlled Analgesia device will be collected and compared between groups.

Secondary outcomes

  1. 2. Perioperative pain intensity

    Time frame: 24 hours

    Changes in the Numerical Rating Scale (NRS) will be recorded at rest and during movement. The participant's baseline NRS will be recorded, followed by measurements before and after neuraxial positioning and up to 24 hours post-surgery. The NRS is a unidimensional measure of pain intensity in adults. It is a segmented numerical version of the Visual Analog Scale (VAS) where the participant selects a whole number (0-10) that best represents the intensity of their pain. The 11-point numerical scale ranges from '0' representing one end of the pain spectrum (e.g. 'no pain') to '10' representing the other end (e.g. 'worst imaginable pain').

  2. Quality of recovery 15 scale

    Time frame: 24 hours after surgery

    Postoperative Quality of Recovery 15 in Turkish scale. The QoR-15 (Quality of Recovery-15) questionnaire is a simple and practical tool used to assess postoperative recovery. It consists of 15 items, each scored on a numeric scale from 0 to 10, resulting in a total score ranging from 0 to 150. Based on the total score, postoperative recovery is categorized as follows: 136-150: Excellent recovery 122-135: Good recovery 90-121: Moderate recovery 0-89: Poor recovery

  3. Postoperative nausea and vomiting

    Time frame: 24 hours

    Postoperative nausea and vomiting (PONV): During follow-up, patients who experience nausea or vomiting will be evaluated using a verbal descriptive PONV scale (0=None, 1=Mild nausea, 2=Moderate nausea, 3=Single episode of vomiting, 4=More than one episode of vomiting).

Study contacts

Contact information is provided by the study sponsor or research team.

Betül Çiftçi Kurt

CONTACT

[email protected]

HALE KEFELİ ÇELİK

CONTACT

[email protected]

5057242409

Sponsors and collaborators

Lead sponsor

Samsun University

Other

Registry information

Official study title

Postoperative Outcomes of Regional Blocks Performed in Cervical Disc Surgery: A Prospective Observational Study

Important dates

Study start
2026
Primary completion
2027
Study completion
2027
First posted
Jul 9, 2026
Registry last updated
Jul 9, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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