Postoperative New-onset Proteinuria and Adverse Outcomes.

We aimed to assess the association between postoperative new-onset proteinuria, all-cause mortality, and decline in kidney function in Chinese people who underwent surgery. The exposure variable was the dipstick proteinuria values from the initial postoperative urinalysis within 30 days after surgery, categorized as negative, trace, 1+, and ≥2+. The primary outcome was 30-day mortality. The secondary outcomes included 1-year mortality and composite kidney outcome assessed using the postoperative estimated glomerular filtration rate.

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Key information

Conditions

Surgery Female Urogenital Diseases Female Urogenital Diseases and Pregnancy Complications Male Urogenital Diseases Mortality Pathological Conditions, Signs and Symptoms Proteinuria Signs and Symptoms Urination Disorders Urogenital Diseases Urologic Diseases Urological Manifestations

Age range

16 year and older

Sex eligibility

All sexes

Study type

Observational

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

surgery patients

Exclusion criteria

kidney or urinary surgery
missing urinalysis results
dipstick proteinuria indicated a value of "≥ trace" at least once preoperatively
with dialysis, end-stage renal disease, or with urinary tract infection at baseline
missing follow-up information

Treatment and study plan

proteinuria

Other

dipstick proteinuria values negative, trace, 1+, and ≥2+

Primary outcomes

mortality

Time frame: 30-day

Sponsors and collaborators

Lead sponsor

Yaozhong Kong

Other

Registry information

Official study title

Association Between Postoperative New-onset Proteinuria and Adverse Outcomes: a Retrospective Cohort Study.

Important dates

Study start: 2000
Primary completion: 2022
Study completion: 2023
First posted: Apr 1, 2024
Registry last updated: Apr 1, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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Completed