Mortality Score in Elderly Patients With Colon Cancer

CR-POSSUM is one of the most used surgical scores to predict mortality after colorectal surgery. Its main drawback is the requirement of intraoperative variables, whose collection is time-consuming and prevents from obtaining a purely preoperative risk assessment. The primary aim of the study is to develop a new surgical score using preoperative parameters to predict 30-day mortality after colon cancer surgery in the elderly population. The secondary objective is to analyze its efficacy compared to CR-POSSUM.

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Key information

Conditions

Mortality Colon Cancer Colonic Diseases Colonic Neoplasms Colorectal Neoplasms Digestive System Diseases Digestive System Neoplasms Gastrointestinal Diseases Gastrointestinal Neoplasms Intestinal Diseases Intestinal Neoplasms Neoplasms Neoplasms by Site Surgery

Age range

80 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Bruno Nardo, Bologna, Italy

About this study

Patients aged 80 and older undergoing surgery for colon cancer from 2011 to 2017 in an Italian hospital were retrospectively selected. MECC score [Mortality in Elderly patients with Colon Cancer] was calculated summing up the scores relating to: arterial saturation of O2, Systolic Blood Pressure, Heart Rate, WBCs, Albumin, Creatinine. Once CR-POSSUM was calculated, the two scores were compared.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Patients aged 80 and above having elective and emergency colonic resection for colon cancer via open, laparoscopic and converted approaches

Exclusion criteria

Surgical resections for rectal cancer and surgical procedures for non-neoplastic colon pathologies

Treatment and study plan

Colon surgery

Procedure

Right, left colon surgery, transverse colon surgery, multiple colon surgery in open and minimally invasive surgert

Primary outcomes

New surgical score using preoperative parameters to predict 30-day mortality after colon cancer surgery in the elderly population

Time frame: Up to 30 days after surgery

MEC Score (arterial saturation of O2, Systolic Blood Pressure, Heart Rate, WBCs, Albumin, Creatinine) for the evaluation of the risk of in-hospital mortality occurred during hospitalization up to 30 days

Sponsors and collaborators

Lead sponsor

University of Bologna

Other

Registry information

Official study title

Score for the Prediction of Mortality Risk After Surgery for Colon Cancer in a Case Series of Elderly Patients

Acronym: MECC

Important dates

Study start: 2011
Primary completion: 2017
Study completion: 2019
First posted: Sep 4, 2020
Registry last updated: Sep 4, 2020

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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Completed