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OpenTrials
Completed

NCT Number: NCT01059331

Postoperative Analgesia After Laparoscopic Living Donor Nephrectomy

The aim of the study is to investigate if perioperative administration of pregabalin vil reduce postoperative pain and the postoperative need for intravenous opioids compared with todays standard treatment which consist of paracetamol, corticoids and ketobemidone.

In addition potential sideeffects as sedation and effect on cognitive function will be recorded.

Completed

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Key information

Conditions

Living Donors

Age range

18 year–75 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 4

Primary location

Oslo Universitetssykehus, Rikshospitalet

Oslo, N-0027, Norway

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • >18, < 75 years
  • healthy patients accepted for laparoscopic living donor nephrectomy

Exclusion criteria

  • not familiar to the Norwegian language (spoken and written)
  • allergic to one or more of the medication given in the study

Treatment and study plan

Pregabalin

Drug

150 mg x 2 daily for 2 days

Other names: Lyrica ATC-nr.: NO3A X 160

Sugar pill

Drug

1 tablet x 2 daily, for 2 days

Primary outcomes

  1. Opioid consumption in milligrams Pain Score given as Numeric Rating Scale (NRS)

    Time frame: Daily troughout the hospital stay, approx. 6 days

Secondary outcomes

  1. Sedation and cognitive function

    Time frame: Daily troughout the hospital stay, approx. 6 days

Sponsors and collaborators

Lead sponsor

Oslo University Hospital

Other

Registry information

Official study title

Perioperative Administration of Pregabalin in Laparoscopic Living Donor Nephrectomy (L-LDN) - an Adjuvance to Peroral Analgetic Treatment - a Randomized Controlled Study

Important dates

Study start
2010
Primary completion
2011
Study completion
2012
First posted
Jan 29, 2010
Registry last updated
Mar 21, 2014

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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