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NCT Number: NCT05882591

Posteromedial Tibiofemoral Incongruence (PMTFI) Treatment

The aim of this study is to assess outcomes of Posteromedial Tibiofemoral Incongruence (PMTFI) Treatment

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Key information

Age range

18 year–70 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Artromedical Orthopaedic Clinic

Bełchatów, Łódź Voivodeship, 97-400, Poland

Location status: Recruiting

Location contact

Konrad Malinowski, MD PhD

CONTACT

[email protected]

+48 509 812 212

About this study

The aim of this study is to assess outcomes of Posteromedial Tibiofemoral Incongruence (PMTFI) Treatment by the means of published technique (reference nr 1).

A decrease in the posterior curvature of the femoral metaphysis close to the medial femoral condyle is one of the anatomical alterations that can be seen within the knee joint. When the knee is fully flexed, this curve is typically concave enough to accommodate the posterior horn of the medial meniscus (PHMM). Similar to cam incongruence in the hip joint, a decrease in curvature may cause posteromedial tibiofemoral incongruence, a condition marked by compression of the PHMM in complete knee flexion. If deep knee flexion occurs, clinical symptoms may appear, and PHMM degeneration may be shown to worsen over time. Surgery may be recommended for patients for whom activity modification and conservative therapy have failed. Our team proposed an arthroscopic procedure that allows for the least amount of correction that is still necessary while also providing final intraoperative confirmation of the clinical need to repair posteromedial tibiofemoral incongruence.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Pain, snapping or discomfort in posterior part of the knee in deep knee flexion during squat
  • Reduced concavity of the femoral metaphysis proximal to the medial femoral condyle confirmed on MRI
  • Impingement of posterior horn of medial meniscus with the metaphysis of femur during full knee flexion confirmed arthroscopically

Exclusion criteria

  • Active knee inflammation
  • Chondral injuries ICRS 3-4
  • Extraarticular reasons of pain, snapping or discomfort in posterior part of the knee in deep knee flexion during squat
  • Cyst or avascular changes within the femoral metaphysis adjacent to the planned localization of the procedure

Treatment and study plan

Posteromedial Tibiofemoral Incongruence (PMTFI) Treatment by the means of published technique (reference nr 1).

Procedure

Posteromedial Tibiofemoral Incongruence (PMTFI) Treatment by the means of published technique (reference nr 1).

Primary outcomes

  1. Presence of pain in full knee flexion

    Time frame: At the 12 month of the follow-up

    Presence of pain in full knee flexion - deep squat: pain yes/no

  2. Presence of pain in full knee flexion

    Time frame: At the 24 month of the follow-up

    Presence of pain in full knee flexion - deep squat: pain yes/no

Secondary outcomes

  1. The functional assessment with the The International Knee Documentation Committee Questionnaire (IKDC)

    Time frame: At the 12 month of the follow-up

    Min of 0 max of 87 points, higher scores mean a better outcome

  2. The functional assessment with the The International Knee Documentation Committee Questionnaire (IKDC)

    Time frame: At the 24 month of the follow-up

    Min of 0 max of 87 points, higher scores mean a better outcome

  3. The functional assessment with the Knee injury and Osteoarthritis Outcome Score (KOOS)

    Time frame: At the 12 month of the follow-up.

    Min of 0 max of 100 points, higher scores mean a better outcome

  4. The functional assessment with the Knee injury and Osteoarthritis Outcome Score (KOOS)

    Time frame: At the 24 month of the follow-up.

    Min of 0 max of 100 points, higher scores mean a better outcome

Study contacts

Contact information is provided by the study sponsor or research team.

Konrad Malinowski, MD PhD

CONTACT

[email protected]

+48 509812212

Sponsors and collaborators

Lead sponsor

Artromedical Konrad Malinowski Clinic

Other

Registry information

Important dates

Study start
2020
Primary completion
2026
Study completion
2027
First posted
May 31, 2023
Registry last updated
May 31, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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