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Completed

NCT Number: NCT00665015

Pleural Effusion Following Cardiac Surgery: Prevalence, Risk Factors and Clinical Features

Pleural effusion is a common complication of cardiac surgery. The aim of this study was to determine the prevalence, characteristics and determinants of clinically significant pleural effusions, defined as those requiring therapeutic pleural drainage.

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Key information

Conditions

Pleural Effusion Coronary Artery Bypass Pleural Diseases Respiratory Tract Diseases

Sex eligibility

All sexes

Study type

Observational

Primary location

Unité de Recherche en Pneumologie, Hôpital Laval

Québec, Quebec, G1V4G5, Canada

About this study

This was a retrospective cohort study of prevalence and characteristics of patients who had a pleural effusion after coronary artery bypass graft, valve replacement or both procedures.

Information was collected on all consecutive patients who underwent CABG surgery and/or valve replacement between January 1, 2004 and December 31, 2005. Demographic information, anthropometric parameters, cardiac and renal function assessments, and comorbid conditions were retrieved from medical files. We also collected data on the type of procedure, whether it was elective or urgent, the number and origin of the grafts, the duration of surgery and of cardiopulmonary bypass and the postoperative complications, including pleural effusions. Clinical presentation and evolution of the effusions as well as pleural fluid characteristics were also studied.

Patients were considered to have a clinically significant pleural effusion when they met at least one of the following criteria: need for thoracentesis, a pleural drainage tube or a hospital readmission due to a pleural effusion that occurred within one year of surgery.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Coronary artery bypass grafting (CABG)
  • Valve replacement
  • Combined CABG and valve replacement
  • between January 1st, 2004 and December 31st, 2005

Exclusion criteria

  • Previous CABG
  • Pulmonary and/or aortic artery surgery
  • Heart or lung transplant
  • Pleural effusion present at the time of surgery

Treatment and study plan

Primary outcomes

  1. Pleural effusion requiring therapeutic drainage

    Time frame: within the first 12 months after surgery

Sponsors and collaborators

Lead sponsor

Laval University

Other

Registry information

Official study title

Pleural Effusions Following Cardiac Surgery: Prevalence, Risk Factors and Clinical Features.

Important dates

Study start
2004
Primary completion
2005
Study completion
2006
First posted
Apr 23, 2008
Registry last updated
Apr 23, 2008

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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