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Completed

NCT Number: NCT03231072

Pleural Effusion Drainage in Mechanically Ventilated Patients Monitored by EIT

Evacuation of pleural effusion (PE) represents a disputable therapy in mechanically ventilated patients. Patients on mechanical ventilation indicated by the physician to pleural fluid evacuation will be monitored throughout the procedure by electrical impedance tomography (EIT) and concurrently end-expiratory lung volume (EELV) will be measured in order to describe impact of PE evacuation on aeration and ventilation of the lungs.

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Key information

Conditions

Pleural Effusion Drainage Electric Impedance Tomography Pleural Diseases Respiratory Tract Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

The Military University Hospital

Prague, 16902, Czechia

About this study

Critically ill patients treated in intensive care units have a disorder of distribution and volume of body fluids due to principal illness and some therapeutic interventions. One of its manifestations is pleural effusion (PE) formation.

Patients on mechanical ventilation indicated by treating physician to pleural fluid evacuation will be monitored throughout the procedure by electrical impedance tomography (EIT) and concurrently end-expiratory lung volume (EELV) will be measured. The purpose of the study is to better understand impact of PE evacuation on aeration and ventilation of the lungs.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • mechanical ventilation, presence of pleural effusion, decision of the treating physician to drain it

Exclusion criteria

  • impossibility to apply EIT belt or to find suitable save point for drainage when the EIT belt is attached
  • standard EIT exclusion criteria according to the device manufacturer

Treatment and study plan

Electrical Impedance Tomography record

Device

Monitoring of pleural effusion evacuation by means of EIT

Primary outcomes

  1. Change of the thorax electrical impedance following pleural effusion drainage in mechanically ventilated patients

    Time frame: 4 hours

    Comparison of EIT results with end-expiratory lung volume measurement during drainage of pleural effusion

Secondary outcomes

  1. Change of the distribution of ventilation following pleural effusion drainage in mechanically ventilated patients

    Time frame: 4 hours

    Change of distribution of ventilation over EIT regions of interest (ROIs)

Sponsors and collaborators

Lead sponsor

Czech Technical University in Prague

Other

Collaborators

  • Military University Hospital, Prague

Registry information

Official study title

Effects of the Pleural Effusion Drainage in Mechanically Ventilated Patients Monitored by Electrical Impedance Tomography and End-Expiratory Lung Volume

Important dates

Study start
2017
Primary completion
2018
Study completion
2022
First posted
Jul 27, 2017
Registry last updated
Jul 22, 2022

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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