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Completed

NCT Number: NCT01758094

Plasma RBP Levels in Patients With Idiopathic Hypogonadotrophic Hypogonadism

The aim of the present study was to demonstrate the RBP4 levels, association of RBP4 with insulin resistance and influence of testosterone treatment on this cytokine in patients with idiopathic hypogonadotropic hypogonadism.

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Key information

Conditions

Idiopathic Hypogonadotropic Hypogonadism Endocrine System Diseases Gonadal Disorders Hypogonadism

Age range

19 year–26 year

Sex eligibility

Male

Study type

Observational

Primary location

Gulhane School of Medicine Dep. of Endocrinology and Metabolism

Ankara, 06018, Turkey (Türkiye)

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

decreased serum testosterone concentration below the normal range (serum T < 300ng/dL), FSH and LH levels within or below the normal range, absence of a pituitary or hypothalamic mass lesions on MRI, presence of gonadotropin response to repetitive doses of GnRH, normal smell test and normal karyotypes

Exclusion criteria

previous androgen treatment, history of smoking, presence of bilateral anorchia, intellectual deficiency, diabetes mellitus, arterial hypertension or dyslipoproteinemia, medication of any kind and drug abuse. Because of possible confounding effects, patients with other hormone deficiencies were excluded.

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Treatment and study plan

Sustanon 250 mg ampule (Testosterone esters)

Drug

Drug used for treatment of hypogonadism

Other names: No name

Primary outcomes

  1. Retinol binding protein 4, hs-CRP levels in patients with idiopathic hypogonadotrophic hypogonadism

    Time frame: 2008-2012

Secondary outcomes

  1. Effect of testosterone treatment on retinol binding globulin 4 and hs-CRP levels in patients with hypogodotrophic hypogonadism

    Time frame: 2008-2012

Sponsors and collaborators

Lead sponsor

Gulhane School of Medicine

Other

Registry information

Important dates

Study start
2008
Primary completion
2012
Study completion
2012
First posted
Jan 1, 2013
Registry last updated
Jan 3, 2013

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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