Physiological Responses in Tobacco Chippers

This study will analyze a series of biological and behavioral markers in different populations of smokers. The study groups will differ in their cigarette consumption and level of nicotine dependence. This analysis will help to identify factors that might be important for smoking behavior and nicotine addiction. The results from this study will contribute to improve campaigns for smoking prevention and treatments for smoking cessation.

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Key information

Conditions

Smoking Behavior Stress

Age range

25 year–55 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Oregon Health and Science University

Portland, Oregon, 97239, United States

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

healthy adults
age 25-55

Exclusion criteria

alcohol or drug addiction
unstable significant medical problems
neurologic disease
medications known to affect CNS function or impact physiologic parameters measured in the study
significant visual impairment
breath carbon monoxide (BCO) level of less than 10 ppm for smokers
breath carbon monoxide (BCO) level of more than 5 ppm for non-smokers
for heavy regular smokers: erratic smoking history (i.e. they must have smoked an average of 15 cigarettes daily for at least one year)

Treatment and study plan

Primary outcomes

Electroencephalography

Time frame: Changes from baseline during a hard cognitive task

Electroencephalography will be measured during performance on a hard cognitive task.

Secondary outcomes

Salivary cortisol

Time frame: Changes from baseline during performance on a hard cognitive task

Salivary cortisol will be measured at baseline, during a hard cognitive task and 30 minutes after the cognitive task.

Sponsors and collaborators

Lead sponsor

Oregon Health and Science University

Other

Registry information

Official study title

Physiological Responses in Tobacco Chippers (Non Nicotine-dependent Light Smokers)

Important dates

Study start: 2010
Primary completion: 2013
Study completion: 2013
First posted: Nov 10, 2010
Registry last updated: Oct 30, 2014

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed