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Completed

NCT Number: NCT05490927

Ethnic Microaggressions and Smoking Behaviors Among Latinx Adults

The purpose of this study is to examine whether microaggressions relate to multimodal facets of smoking behavior, subjective withdrawal, and urge/craving. Additionally, the second aim is to examine whether smoking deprivation moderates the relation between microaggressions and multiple facets of smoking behavior, subjective withdrawal, and urge/craving.

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Key information

Conditions

Smoking Behavior Discrimination, Racial Prejudice Racism Social Behavior Social Discrimination

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

RESTORE Laboratory: Research on Emotion, Substance Treatment Outcomes, and Racial Equity

Houston, Texas, 77204, United States

About this study

This proposal will employ a novel multi-modal approach to evaluate the role of microaggressions in relation to smoking lapse and topography among a sample of Latinx smokers. Adult Latinx daily smokers will attend two counterbalanced experimental sessions - (1) smoking deprivation (16 hours of smoking abstinence) and (2) smoking as usual - during which microaggressions during the relapse analog task will be assessed.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Being 18 years of age or older
  • Current regular (daily) cigarette smoking for >= 1 year
  • Current smoking >= 5 cig/day and biochemically confirmed via carbon monoxide (CO) analysis
  • Being self-identified as Hispanic or Latino
  • Able to provide written, informed consent
  • Endorsement of at least one microaggression experience over the past 6-months

Exclusion criteria

  • Endorsement of current psychotic symptoms
  • Active suicidality
  • Currently pregnant

Treatment and study plan

Microaggression Recall and Relapse Analogue Task

Behavioral

Participants will engage in a microaggression recall task followed by the McKee Experimental Relapse Analogue Task

Primary outcomes

  1. Smoking Behaviors

    Time frame: During the Smoking as Usual Visit and Smoking Deprivation Visit (Visits are randomly ordered, counterbalanced separated by ~14 days)

    Smoking behaviors will be operationally defined as smoking topography (e.g., puff behavior) measured via the Clinical Research Support System (CReSS; Plowshare Technologies, Borgwaldt KC, Inc., Virginia).

  2. Subjective Withdrawal

    Time frame: During the Smoking as Usual Visit and Smoking Deprivation Visit (Visits are randomly ordered, counterbalanced separated by ~14 days)

    The 8-item Minnesota Withdrawal Scale will be used to assesses withdrawal severity. Each of the items are rated on a Likert-type scale ranging from 0 to 4. Items are summed to produce a total score with higher scores indicative of worse outcomes (possible range 0-32).

  3. Urge/Craving

    Time frame: During the Smoking as Usual Visit and Smoking Deprivation Visit (Visits are randomly ordered, counterbalanced separated by ~14 days)

    Smoking urge/craving will be measured with the 10-item Questionnaire of Smoking Urges-Brief (QSU-B). Each of the items are rated on a Likert-type scale ranging from 1 to 7. Items are summed to create two subscale scores and a total score with higher scores indicative of worse outcomes (possible range 7-70).

  4. Smoking Lapse Behaviors

    Time frame: During the Smoking as Usual Visit and Smoking Deprivation Visit (Visits are randomly ordered, counterbalanced separated by ~14 days)

    Smoking Lapse Behaviors will be measured during the Relapse Analogue Task (RAT), during which participants are able to delay smoking for a small financial reward. For this task, Smoking Lapse Behaviors are conceptualized as two variables: (a) minutes in time of smoking delay (possible range -50 to +50) and (b) number of cigarettes smoked

Sponsors and collaborators

Lead sponsor

University of Houston

Other

Registry information

Official study title

Latinx Smokers: Evaluating Ethnic Microaggressions on Smoking Behavior and Relapse

Important dates

Study start
2022
Primary completion
2026
Study completion
2026
First posted
Aug 8, 2022
Registry last updated
Jun 22, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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