Skip to main content
OpenTrials
Completed

NCT Number: NCT03244761

Physiological Effects of High-Flow Tracheal Oxygen Via An Modified Interface

Tracheostomy is often performed in patients after or anticipated prolonged mechanical ventilation, who are usually required oxygen therapy after discontinuation of mechanical ventilation.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Tracheostomy

Age range

18 year–80 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Jian-Xin Zhou

Beijing, Beijing Municipality, 100050, China

About this study

Tracheostomy is often performed in patients after or anticipated prolonged mechanical ventilation, who are usually required oxygen therapy after discontinuation of mechanical ventilation.The high-flow tracheal (HFT) oxygen therapy in tracheostomized patients has been shown that can improve oxygenation,but can not induce positive end-expiratory pressure and elevation of end-expiratory lung volume. A modified HFT system by increasing expiratory resistance might induce PEEP and consequently elevate EELV.

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • The tracheostomized patient requiring the convenient oxygen therapy.

Exclusion criteria

  • Under 18 years;
  • history of esophageal, gastric or lung surgery;
  • The contraindication of using EIT (pacemaker, defibrillator, and implantable pumps).

Treatment and study plan

The modified HFT

Procedure

The HFT was modified by increasing the expiratory resistance.

Primary outcomes

  1. The mean end expiratory pressure.

    Time frame: the last 1 minutes of steady breathing during the standard or modified HFT.

    The patients was delivering the high flow oxygen via the standard and modified HFT interface for 20 minutes.

Secondary outcomes

  1. Changes in global and regional EELV

    Time frame: the last 1 minutes of steady breathing during the standard or modified HFT.

    The Electrical impedance tomography (EIT) was applied in monitoring the change of EELV at the bedside.

Sponsors and collaborators

Lead sponsor

Capital Medical University

Other

Registry information

Official study title

Physiological Effects of High-Flow Tracheal Oxygen Via An Modified Interface in Tracheostomized Patients

Important dates

Study start
2017
Primary completion
2017
Study completion
2018
First posted
Aug 10, 2017
Registry last updated
Feb 12, 2018

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.