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OpenTrials
Completed

NCT Number: NCT02054962

Persistent Pain Among Elderly Experiencing Motor Vehicle Collision

Chronic problems after traumatic events are common in non-elderly adults. Previous studies have shown that after minor motor vehicle collision (MVC), 10-30% of non-elderly adult patients develop chronic regional pain (neck or back pain). In addition, up to 1/3 of non-elderly adults will develop psychological sequelae, including posttraumatic stress disorder, depression, and anxiety disorders. There have been no prospective studies examining the frequency or predictors of persistent pain or psychological sequelae in older adults. The proposed study seeks to determine the frequency of persistent pain, psychological sequelae, and associated disability in older adults after minor MVC trauma and to identify candidate predictors for a model of adverse outcomes after MVC in this population. 200 individuals over 65 years of age will be recruited from emergency departments in four states with no-fault accident laws. Patients who meet inclusion criteria and who consent to the emergency department (ED) study will undergo a 30-45 minute ED assessment of crash-related, psychosocial, and biological factors, and complete telephone follow-ups at 2 weeks, 6 weeks 6 months, and 12 months. The wealth of information gained from this study will be used to determine the frequency of adverse events in older adults after MVC and to identify high risk elderly patients. These results will inform subsequent development of secondary pharmacologic and/or behavioral interventions to prevent chronic pain and psychological sequelae after traumatic events in older adults.

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Key information

Age range

65 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Spectrum Health - Butterworth Hospital

Grand Rapids, Michigan, 49503, United States

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patient speaks English, presented to ER less than 24 hours after an MVC, patient has an address and telephone

Exclusion criteria

  • Patient
  • is a prisoner,
  • has fractures or an intracranial injury,
  • has injuries that are life threatening or expected to result in hospitalization for more than 72 hours,
  • is receiving end of life, hospice, or comfort care, or
  • is considered ineligible by treating physician.

Treatment and study plan

Primary outcomes

  1. Average pain 6 months after Emergency Department visit

    Time frame: 6 months

    Average pain during the past week with pain measured on a 0-10 scale.

Secondary outcomes

  1. Physical function at 6 months after Emergency Department visit

    Time frame: 6 months

    Function measured on a 0-12 scale based on patient reported ability or difficulty walking, carrying objects, and climbing stairs (Simonsick E, et al. 2001).

Sponsors and collaborators

Lead sponsor

University of North Carolina, Chapel Hill

Other

Collaborators

  • National Institute on Aging (NIA)

Registry information

Official study title

Persistent Pain and Associated Functional Decline Among Elderly Experiencing Motor Vehicle Collision

Acronym: Elderly CRASH

Important dates

Study start
2012
Primary completion
2016
Study completion
2017
First posted
Feb 4, 2014
Registry last updated
Feb 5, 2018

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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