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OpenTrials
Completed

NCT Number: NCT03141164

Peripheral Vision Training Study

This study will train participants (young people and older adults) to do a visual task, and will assess whether this results in changes in behavioral assessments. In some participants, we will be also testing whether MRI measures (cortical thickness, functional connectivity) change with training.

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Key information

Conditions

Visual Impairment Cognitive Change Eye Diseases Nervous System Diseases Neurologic Manifestations Pathological Conditions, Signs and Symptoms Sensation Disorders Signs and Symptoms Vision Disorders

Age range

18 year–89 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

UAB

Birmingham, Alabama, 35294, United States

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Right handed individuals
  • Aged 19-89
  • In good health as self-reported or visual impairments due to partial vision loss
  • Normal or corrected-to-normal vision with contact lenses or visual impairments due to partial vision loss

Exclusion criteria

  • Younger than 18 or older than 89
  • Being hearing-impaired
  • Not in good health except due to partial vision loss
  • Having a previous serious head injury or neurological disorder, or loss of consciousness for more than 2 minutes
  • Having hallucinations or delusions
  • Having a current or past history of a substance abuse disorder
  • Currently taking psychoactive medications

Treatment and study plan

computerized training

Other

Computerized training

Primary outcomes

  1. scores on acuity tests

    Time frame: baseline

    scores on acuity tests

  2. scores on acuity tests

    Time frame: immediately following training

    scores on acuity tests

  3. scores on spatial attention tests

    Time frame: baseline

    scores on spatial attention tests

  4. scores on spatial attention tests

    Time frame: immediately following training

    scores on spatial attention tests

Secondary outcomes

  1. Changes in cortical thickness

    Time frame: baseline and immediately following training

    Increases in cortical thickness in areas corresponding to trained visual field

  2. Changes in functional connectivity

    Time frame: baseline and immediately following training

    Changes in functional connectivity of areas corresponding to trained visual field

Sponsors and collaborators

Lead sponsor

University of Alabama at Birmingham

Other

Registry information

Acronym: PVTS

Important dates

Study start
2017
Primary completion
2020
Study completion
2020
First posted
May 4, 2017
Registry last updated
Jun 8, 2021

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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