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NCT Number: NCT07237321

Peripheral Magnetic Stimulation of Foot Muscles: Effects on Medial Longitudinal Arch Height and Foot Muscle Strength in Adults With Flat Feet

This study examines the effects of repetitive peripheral magnetic stimulation (rPMS) on foot invertor muscle strength, morphology, and the height of the medial longitudinal arch (MLA) in individuals with flat feet. The rPMS will be applied non-invasively to the extrinsic and intrinsic foot muscles three times per week for twelve weeks. The experimental group will receive rPMS targeting the invertor muscles of the foot, while the control group will not receive stimulation but will follow the same measurement schedule.

Assessments will be performed at baseline, after 6 weeks, and after 12 weeks of intervention. The primary outcome will be the change in the height of the MLA, evaluated using dynamic navicular drop assessment during gait. Secondary outcomes will include changes in the isometric inversion torque of the foot invertors and morphological adaptations of the tibialis posterior muscle assessed by ultrasound imaging.

This study seeks to determine whether rPMS can improve the height of the MLA, foot invertor muscle strength and structural stability in adults with flat feet. The findings may contribute to developing new, non-invasive therapeutic approaches for improving foot function and preventing musculoskeletal imbalances related to flat foot deformity.

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Key information

Age range

18 year–50 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Faculty of Sport, University of Ljubljana, Ljubljana, Slovenia

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About this study

During movement, the role of the foot muscles is often overlooked. Through their strength and stabilizing function, foot muscles play an important role in maintaining balance, posture, and force transmission throughout the body. Proper activation of these muscles also helps preserve the stability of the medial longitudinal arch (MLA), thereby influencing the overall biomechanics of human movement.

The foot muscles are classified as extrinsic (originating outside the foot) and intrinsic (originating and inserting within the foot). Extrinsic muscles, primarily stabilize the ankle joint and control larger movements, whereas intrinsic muscles store and release elastic energy within the foot, contributing to arch support and movement efficiency.

A lowered height or collapsed arch of the foot, known as flat foot (pes planus), is characterized by arch flattening during weight-bearing and affects approximately 13-27% of the adult population. This deformity alters force distribution and shock absorption, increasing mechanical load on the joints and muscles of the lower kinetic chain. Consequently, flat feet are often associated with foot pain, tendinopathies, and different musculoskeletal disorders in the knees, hips, and lumbar spine.

One of the main causes of flat foot deformity is dysfunction of the tibialis posterior (TP) tendon. This dysfunction leads to reduced muscle strength, decreased neuromuscular activation of the foot invertors and plantar flexors, and subsequent lowering of the navicular bone, resulting in a reduced MLA height. Strengthening the m. TP not only maintains arch position but also improves gait efficiency by reducing compensatory activation of other muscles. This muscle is considered as the strongest foot invertor and has the largest moment arm along the subtalar axis.

Recent research highlights that strengthening foot invertor muscles, particularly m. TP, can effectively increase height of the MLA. Conventional interventions include specific exercise programs and proprioceptive neuromuscular facilitation techniques. However, neuromuscular electrical stimulation used in previous studies did not showed significant increases in MLA height, partly due to pain and discomfort during deep muscle stimulation.

Repetitive peripheral magnetic stimulation (rPMS) has emerged as a promising non-invasively alternative, capable of stimulating deep neuromuscular structures. Several studies have shown that high-frequency rPMS can induce muscle activation, transient swelling, and potential hypertrophy indicators. Nevertheless, there is limited evidence on the long-term (multi-week) effects of rPMS on deep muscles such as the m. TP.

Aim of this research is to implement a 12-week rPMS protocol targeting both extrinsic and intrinsic foot invertor muscles, and to examine whether rPMS induces changes in the height of the MLA. Additionally, the study aims to determine whether 12-week rPMS protocol contributed to increased strength and cross-sectional area of the m. TP.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age between 18 and 50 years,
  • functionally flat feet of participants.

Exclusion criteria

  • Acute leg injuries,
  • diabetes,
  • vascular disorders of the lower limbs,
  • open wounds or skin lesions on the lower leg or foot,
  • participants with metal implants near the stimulation site,
  • cardiac pacemaker,
  • other orthopedic or neurological conditions that could affect the study results or pose a health risk to the participants.

Treatment and study plan

Repetitive Peripheral Magnetic Stimulation (rPMS)

Device

Repetitive peripheral magnetic stimulation (rPMS) will be applied to the foot invertor muscles three times per week for 12 weeks. Stimulation will target the upper third of the anteromedial side of the shin, near the tibia, using an oval magnetic coil. To ensure correct coil placement, visible muscle contraction and ankle inversion will be monitored. Intrinsic foot muscles will be simultaneously stimulated using a foot stimulator, with the nondominant foot positioned on the stimulation platform. Participants will perform isometric inversion contractions during rPMS to enhance neuromuscular activation and short-foot exercises to engage local foot stabilizers.

Other names: Peripheral Magnetic Stimulation, rPMS, FMS, Functional Magnetic Stimulation

Primary outcomes

  1. Change in medial longitudinal arch height

    Time frame: Baseline (Day 1), Week 6, Week 12

    Measuring dynamic navicular drop assessment during the stance phase of gait.

Secondary outcomes

  1. Change in isometric inversion torque of the stimulated foot

    Time frame: Baseline (Day 1), Week 6, Week 12

    Measured using an special designed isometric device to assess maximal voluntary torque during foot inversion in subtalar exis.

Other outcomes

  1. Change in cross-sectional area of the tibialis posterior muscle

    Time frame: Baseline (Day 1), Week 6, Week 12

    Measured using ultrasound imaging to evaluate morphological adaptations of the tibialis posterior muscle and/or other foot invertor muscles.

Study contacts

Contact information is provided by the study sponsor or research team.

Rok Bavdek, PhD

CONTACT

[email protected]

0038641866285

Sponsors and collaborators

Lead sponsor

University of Ljubljana

Other

Collaborators

  • University of Ljubljana, Faculty of Medicine

Registry information

Official study title

Peripheral Magnetic Stimulation of Foot Muscles

Acronym: rPMS-Foot

Important dates

Study start
2025
Primary completion
2027
Study completion
2027
First posted
Nov 19, 2025
Registry last updated
Jun 2, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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