Peripheral Artery Disease in Regular Hemodialysis Patients

Recent studies have reinforced the association between high NLR and PAD in hemodialysis patients. This highlights the need for further studies to confirm its predictive value and determine optimal cut-off thresholds tailored to local patient populations. Accordingly, the present study aims to investigate the relationship between NLR and the presence of PAD in patients undergoing regular hemodialysis. By establishing this association in a well-defined population, we hope to provide evidence that supports the use of NLR as a simple, cost-effective tool for PAD risk stratification and early intervention

Active, Not Recruiting

This study is active but is not currently recruiting participants.

Key information

Conditions

Chronic Kidney Disease Chronic Disease Disease Attributes Female Urogenital Diseases Female Urogenital Diseases and Pregnancy Complications Kidney Diseases Male Urogenital Diseases Pathologic Processes Pathological Conditions, Signs and Symptoms Renal Insufficiency Renal Insufficiency, Chronic Urogenital Diseases Urologic Diseases

Sex eligibility

All sexes

Study type

Observational

Primary location

Sohag faculty

Sohag, Egypt

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Adult patients aged ≥18 years.
Undergoing maintenance hemodialysis for at least 3 months (thrice weekly)
Able to provide informed consent.
Willing to undergo clinical and laboratory evaluations, including peripheral vascular assesment

Exclusion criteria

Active infection or sepsis at the time of evaluation

.* Patients who have a sedimentation rate of more than 60 mm/hour

*. Known autoimmune or hematologic disorders that may influence leukocyte count.

Current use of immunosuppressive therapy, corticosteroids, or chemotherapy.5. History of malignancy.6. Patients with incomplete medical records or unable to undergo peripheral vascular assessment.

Treatment and study plan

Primary outcomes

The aim of this study is to evaluate the predictive value of the neutrophil-to- lymphocyte ratio (NLR) for the presence of peripheral artery disease (PAD) in patients undergoing regular hemodialysis.

Time frame: 6months
% of patients with affection in neutrophills to lymphocytes ratio in parient on regular hemodialysis.

Time frame: 6 months

Sponsors and collaborators

Lead sponsor

Sohag University

Other

Registry information

Official study title

Relation Between Neutrophil to Lymphocyte Ratio and Peripheral Artery Disease in Regular Hemodialysis Patients at Sohag University Hospital

Important dates

Study start: 2025
Primary completion: 2026
Study completion: 2026
First posted: Sep 17, 2025
Registry last updated: Sep 17, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Active, Not Recruiting