Perforator Artery Changes During Suprafascial Pre-expansion of the Perforator Flaps

Tissue expansion methods have been recommended as a means of improving the clinical results with perforator flaps but in plastic surgery literature there are few clinical trials supporting this opinion. The purposes of this clinical study are to address the ''preexpanded perforator flap concept'' by demonstrating a case series of relevant reconstructive procedures and to evaluate the perforator vessel changes that happen during the expansion periods of various perforator flap donor sites.

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Key information

Conditions

Scar Cicatrix Contracture Fibrosis Flap Disorder Joint Diseases Muscular Diseases Musculoskeletal Diseases Pathologic Processes Pathological Conditions, Signs and Symptoms

Age range

6 year–60 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

patients with broad scars and contracture bands
patients with esophagocutaneous fistula
patients with ambiguous genitalia

Exclusion criteria

none

Treatment and study plan

preexpanded perforator flap surgery

Procedure

Primary outcomes

Transferred tissue dimensions

Time frame: At least five months after the operation

Demonstrating the amount of transferred healthy tissue exhibits the success of the technique.

Secondary outcomes

Diameter of the perforator artery in a particular tissue level

Time frame: Measured the day before the expander implantation surgery and the day before the flap transfer surgery (second session following tissue expansion)

This measurement will reveal one of the morphologic changes happen during tissue expansion period (perforator flap preexpansion). This measurement will be done for the last six patients. The diameter of the perforator artery of the preexpanded flap will be compared with both the diameter of the same artery before the expansion process and the diameter of the equivalent perforator artery of the symmetric side (non expanded side)of the body.

Sponsors and collaborators

Lead sponsor

Istanbul University

Other

Registry information

Important dates

Study start: 2009
Primary completion: 2013
Study completion: 2013
First posted: Jan 28, 2013
Registry last updated: Jan 29, 2013

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed