Pentraxin-3 in Hysterectomy Patients

Acute trauma and major surgeries activate a series of cascades to evoke systemic inflammatory response. The magnitude of the resulting inflammatory response is proportional to the severity of the tissue trauma. Abdominal or laparoscopic technique is widely used for the purpose of hysterectomy surgery. It is crucial for many aspects to compare these two techniques of hysterectomy in terms of the surgery-induced trauma.

In this study, the severity of the inflammatory response resulting from the tissue trauma due to the techniques of TLH+BSO and TAH+BSO applied in our department were compared based on the PTX-3 molecule.

Inclusion criteria

·TLH+BSO patients and TAH+BSO patients

Exclusion criteria

• History of a chronic disease (coronary artery disease, diabetes mellitus, hypertension, coronary liver failures, chronic kidney disease, chronic respiratory diseases, connective tissue disorders) which may affect levels of PTX-3 and other inflammatory markers.
• Prior surgery due to malignancy.
• History of an intra-abdominal surgery, except for cesarean section.
• History of any disease which may lead to intra-abdominal adhesions (endometriosis, past pelvic infection).