Patient Perspectives Throughout Peri-Implantitis Treatment

Change in oral health-related quality of life throughout peri-implantitis treatment, assessed using the Spanish version of the Oral Health Impact Profile-14 (OHIP-14sp). The total OHIP-14sp score ranges from 0 to 56, with higher scores indicating worse oral health-related quality of life. The outcome will be expressed as the total OHIP-14sp score and compared across the four study time points.

Unit of Measure: OHIP-14sp total score (0-56)

Pain perceived by the patient during each stage of peri-implantitis treatment, measured using a 100-mm visual analogue scale (VAS), where 0 indicates no pain and 100 indicates the worst imaginable pain Unit of Measure: Millimeters (0-100 mm VAS)

Anxiety and concern perceived by the patient in relation to the diagnosis of peri-implantitis and its treatment, measured using a 100-mm visual analogue scale (VAS), where 0 indicates no anxiety or concern and 100 indicates the highest imaginable level of anxiety or concern.

Unit of Measure: Millimeters (0-100 mm VAS)

Emotional impact perceived by the patient in relation to the diagnosis of peri-implantitis and its treatment, including feelings such as fear of implant loss and frustration with the diagnosis, measured using a 100-mm visual analogue scale (VAS), where 0 indicates no emotional impact and 100 indicates the highest imaginable emotional impact.

Unit of Measure: Millimeters (0-100 mm VAS)

Patient satisfaction with the treatment received for peri-implantitis, measured using a 100-mm visual analogue scale (VAS), where 0 indicates no satisfaction and 100 indicates the highest possible level of satisfaction.

Unit of Measure: Millimeters (0-100 mm VAS)

Patient-perceived oral function following peri-implantitis treatment, including the ability to chew, speak, and perform oral hygiene, measured using a 100-mm visual analogue scale (VAS), where 0 indicates complete functional impairment and 100 indicates normal oral function.

Unit of Measure: Millimeters (0-100 mm VAS)

Patient perception of the extent to which the outcomes of peri-implantitis treatment met their initial expectations, measured using a 100-mm visual analogue scale (VAS), where 0 indicates that the treatment outcomes did not meet expectations at all and 100 indicates that the treatment outcomes completely met or exceeded expectations.

Unit of Measure: Millimeters (0-100 mm VAS)

Patient perception of the aesthetic outcome following surgical treatment for peri-implantitis, measured using a 100-mm visual analogue scale (VAS), where 0 indicates complete dissatisfaction with the aesthetic outcome and 100 indicates complete satisfaction with the aesthetic outcome.

Unit of Measure: Millimeters (0-100 mm VAS)

Depth of peri-implant sulcus measured at six sites per implant using standardized probing force (20-25 g). Unit of Measure: millimeters (mm)

Radiographic marginal bone level measured in millimeters as the distance from the implant reference point designed to be in intimate contact with the bone to the most coronal bone-to-implant contact on standardized periapical radiographs.

Unit of Measure: Millimeters (mm)

Peri-implant bone defect morphology classified according to the predominant defect configuration as intrabony, suprabony, or combined, based on the intraoperative clinical assessment.

Unit of Measure: Categorical (intrabony, suprabony, combined)

Distance from the mucosal margin to the mucogingival junction at the buccal aspect of the implant, measured using a periodontal probe.

Unit of Measure: Millimeters (mm)

Thickness of the buccal keratinized peri-implant mucosa assessed using the periodontal probe transparency method. The mucosa is classified as thin if the periodontal probe is visible through the tissue (<1 mm) and thick if the probe is not visible (≥1 mm).

Unit of Measure: Categorical (thin [<1 mm] or thick [≥1 mm])

Participant age at baseline (T0), calculated as the interval between the date of birth and the enrollment date.

Unit of Measure: Years, months, and days

Self-reported sex of the participant, recorded at baseline. Unit of Measure: Categorical (Male, Female, Other, Prefer not to disclose)

Self-reported smoking status at baseline. Unit of Measure: Categorical (Never smoker, Former smoker, Current smoker)

Average number of cigarettes smoked per day, self-reported by current and former smokers.

Unit of Measure: Cigarettes/day

Presence of relevant systemic comorbidities based on the participant's self-reported medical history and clinical records.

Unit of Measure: Categorical (Yes/No)

Self-reported frequency of toothbrushing. Unit of Measure: Categorical (Once daily, Twice daily, Three or more times daily)

Type of toothbrush routinely used by the participant. Unit of Measure: Categorical (Manual, Electric, Both)

Primary method used by the participant for interproximal oral hygiene. Unit of Measure: Categorical (Dental floss, Interdental brushes, Oral irrigator, None)

Self-reported frequency of interproximal oral hygiene. Unit of Measure: Categorical (Never, Occasionally, Daily)

Primary reason for the loss of the tooth replaced by the implant, based on the participant's dental history and clinical records.

Unit of Measure: Categorical (Periodontitis, Caries, Endodontic failure, Root fracture, Trauma, Congenital absence, Orthodontic extraction, Other)

Arch in which the implant is located. Unit of Measure: Categorical (Maxilla, Mandible)

Anatomical position of the implant according to its location in the dental arch.

Unit of Measure: Categorical (Anterior, Posterior)

Specific tooth position replaced by the implant, recorded using the FDI tooth numbering system.

Unit of Measure: Tooth number

Commercial brand of the implant. Unit of Measure: Free text

Commercial model of the implant. Unit of Measure: Free text

Type of implant surface according to the manufacturer's specifications. Unit of Measure: Categorical (Treated, Untreated)

Type of implant-prosthetic connection. Unit of Measure: Categorical (Internal, External, Conical, Other)

Type of implant-supported restoration according to its retention mechanism. Unit of Measure: Categorical (Screw-retained, Cement-retained)

Calendar year in which the implant-supported prosthetic restoration was delivered and functionally loaded.

Unit of Measure: Year

Total number of dental implants present in the participant at baseline, recorded to account for patient-level clustering in statistical analyses.

Unit of Measure: Number of implants

Calendar year in which the implant was surgically placed. Unit of Measure: Year

Presence of bleeding and/or suppuration elicited within 30 seconds after gentle probing at six sites per implant using a standardized periodontal probe.

Unit of Measure: Categorical (Present/Absent)

Surgical approach used for the treatment of peri-implantitis, classified according to the primary surgical technique performed.

Unit of Measure: Categorical (Access surgery, Resective surgery, Regenerative surgery, Combined surgery)

Presence of postoperative wound dehiscence at the surgical site, assessed during the postoperative clinical examination.

Unit of Measure: Categorical (Present/Absent)

Occurrence of postoperative complications related to peri-implantitis surgery, including the type of complication when present.

Unit of Measure: Categorical (Absent/Present) and free text (type of complication)