University Hospital
Nantes, 44093, France
Location status: Recruiting
NCT Number: NCT04389463
This study will describe the recovery process of patients undergoing cardiac surgery during the covid-19 pandemic. This will focus on hemodynamic failure and organ dysfunction after surgery.
Capturing real-world data and sharing international experience will inform the management of this complex group of patients who undergo surgery throughout the COVID-19 pandemic, improving their clinical care.
This investigator-led, non-commercial, non-interventional does not collect any patient identifiable information.
Interested in participating?
Request Info18 year and older
All sexes
Observational
Nantes, 44093, France
Location status: Recruiting
Performing cardiac surgery in the context of SARS-CoV2 infection is potentially at risk of marked post-operative hemodynamic failure (shock) due to the inflammatory reaction generated by the surgery and the extracorporeal circulation associated with the viral infection. In addition, in the absence of infection, 30-50% of patients will experience acute post-operative respiratory failure due to the combined effects of extracorporeal circulation and general anesthesia. The pulmonary tropism of the virus therefore is susceptible to increase in post-operative respiratory impairment.
Thus, the infection is likely to favor the occurrence of post-operative shock but also to aggravate respiratory failure and other post-operative organ failures.
Therefore, the investigators designed an observational study that aims at comparing two groups of patients:
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
No description
Time frame: 12 hours post-operatively
The VIS score correlates with mortality after cardiac surgery and reflects the degree of patient hemodynamic failure. This score is calculated as follows:
ISR = Dobutamine dose in g/kg/min + 100 times the Adrenaline dose in g/kg/min + 100 times the Noradrenaline dose in g/kg/min + 10,000 times the Vasopressin dose in U/kg/min.
Time frame: 5 days post-operatively
Prospective assessment of ICU outcomes until all included patients were discharged from ICU
Time frame: 28 days post-operatively
Prospective assessment of ICU outcomes until all included patients.
Contact information is provided by the study sponsor or research team.
Annick COULON
CONTACT
Mickael VOURC'H, MD
CONTACT
Nantes University Hospital
Other
Patient Outcome of Cardiac Surgery During the COVID-19 Pandemic ; International Cohort Study
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
Published trials that share one or more normalized conditions with this study.
NCT05732116
COVID-19, Coronaviridae Infections
Ningbo, Zhejiang, China
View Trial DetailsNCT07157111
COVID - 19, COVID-19
Wuhan, Hubei, China
View Trial DetailsNCT05677815
COVID-19, Coronaviridae Infections
Xi'an, Shaanxi, China
View Trial DetailsNCT05178251
Appendicitis, Appendicitis With Peritonitis
Nancy, France
View Trial Details