Skip to main content
OpenTrials
Completed

NCT Number: NCT07157111

Perioperative Outcomes for Children With Preoperative URTI Symptoms After COVID-19 Pandemic

The goal of this observational study is to investigate the impact of the COVID-19 pandemic on perioperative outcomes in children with preoperative URTI symptoms and to explore whether the COVID-19 pandemic affected the additional surgical risk associated with preoperative URTI symptoms. The main question it aims to answer is the appropriate timing of elective non-cardiac surgery in the post-COVID-19 era.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

URTI COVID - 19 COVID-19 Coronaviridae Infections Coronavirus Infections Elective Non-cardiac Surgery Infections Lung Diseases Nidovirales Infections Pathologic Processes Pathological Conditions, Signs and Symptoms Perioperative Respiratory Adverse Events Pneumonia Pneumonia, Viral Postoperative Complications RNA Virus Infections Respiratory Tract Diseases Respiratory Tract Infections Virus Diseases

Age range

1 year–12 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Tongji Hospital

Wuhan, Hubei, 430030, China

About this study

This study aims to investigate the impact of the COVID-19 pandemic on perioperative outcomes in children with preoperative URTI symptoms and to explore whether the COVID-19 pandemic affected the additional surgical risk associated with preoperative URTI symptoms. The findings will provide evidence-based guidance for optimizing surgical timing decisions in the post-COVID-19 era.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Aged 0-12 years
  • ASA physical status classification I-III
  • Undergoing non-cardiac surgery
  • Children presenting with mild URTI symptoms within 2 weeks before surgery

Exclusion criteria

  • Presenting with severe underlying diseases (e.g., congenital heart disease, immunodeficiency)
  • Presenting with a single symptom of fever that can be explained by other diseases
  • Day surgery
  • Children with abnormal preoperative chest X-rays

Treatment and study plan

Primary outcomes

  1. postoperative complications

    Time frame: 7days

    The postoperative complications including hemorrhage, infection, gastrointestinal complications, respiratory adverse events (RAE), and recurrence of the primary disease.

Secondary outcomes

  1. Intraoperative RAE

    Time frame: 1day

    Intraoperative RAE, including hypercapnia, hypoxemia

  2. Emergence RAE

    Time frame: 1day

    Emergence RAE, including hypercapnia, hypoxemia

  3. PACU stay

    Time frame: 1hour

    Meeting discharge criteria from PACU

  4. Total hospital length of stay

    Time frame: 10days

    Total hospital length of stay

  5. Postoperative length of stay

    Time frame: 7days

    Postoperative hospital length of stay

Sponsors and collaborators

Lead sponsor

aijun xu

Other

Registry information

Official study title

Perioperative Outcomes for Children With Preoperative Upper Respiratory Tract Infection Symptoms in Elective Non-cardiac Surgery After COVID-19 Pandemic at a Large Tertiary Hospital in China: a Retrospective Cohort Study

Acronym: URTI

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
Sep 5, 2025
Registry last updated
Nov 21, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.