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Completed

NCT Number: NCT02051101

Pathogenic Mechanisms of Port Wine Stain and Repository of Port Wine Stain Biopsy Samples

The purpose of this study is to investigate the pathogenic mechanisms of Port Wine Stain, collect biopsy samples and blood samples to characterize exosomes and metabolites from Port Wine Stain.

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Key information

Conditions

Port-Wine Stain Congenital Abnormalities Congenital, Hereditary, and Neonatal Diseases and Abnormalities Skin Abnormalities Skin Diseases Skin and Connective Tissue Diseases

Age range

1 day and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Beckman Laser Institute

Irvine, California, 92612, United States

About this study

The researcher can detect the defects in nervous system innervation to cutaneous blood vessels contribute to the pathogenesis of Port Wine Stain . Unveiling the pathogenic mechanisms of PWS is crucial to the design of new therapeutic strategies and can use the results to improve current PWS therapeutic outcomes.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Male or female of all ages.
  • Not pregnant.
  • Has diagnosis of port wine stain on the arms, legs, chest, bac.
  • Ability to understand and carry out subject instructions.
  • Subject willing to have skin biopsies on port wine stain and normal skin areas.

Exclusion criteria

  • Pregnant women.
  • Port Wine Stain on the face.
  • History of skin cancer.
  • Current participation in an investigational drug evaluation
  • Concurrent use of known photosensitizing drugs.

Treatment and study plan

Biopsy sample from Port Wine Stain Birthmark

Other

Biopsy sample from Port Wine Stain Birthmark

Primary outcomes

  1. Characterization of Port Wine Stain Birthmark tissue sample

    Time frame: up to 4 weeks

Sponsors and collaborators

Lead sponsor

University of California, Irvine

Other

Collaborators

  • Beckman Laser Institute University of California Irvine

Registry information

Important dates

Study start
2013
Primary completion
2019
Study completion
2019
First posted
Jan 31, 2014
Registry last updated
Nov 1, 2022

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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