Parathyroid Reimplantation in Forearm Subcutaneous Tissue During Thyroidectomy: a Simple Way to Avoid Ipoparathyroidism and Evaluate Graft Function

The purpose of this study is to evaluate safety and effectiveness of normal parathyroid tissue reimplantation in forearm subcutaneous tissue in case of accidental removal of parathyroid gland during thyroid surgery.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Thyroid Goiter Endocrine Gland Neoplasms Endocrine System Diseases Goiter Graves Diseases Head and Neck Neoplasms Multinodular Goiter Neoplasms Neoplasms by Site Thyroid Carcinoma Thyroid Diseases Thyroid Neoplasms

Sex eligibility

All sexes

Study type

Observational

Primary location

General Surgery Unit, ICOT Hospital

Latina, 04100, Italy

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Patients affected by benign thyroid disease undergoing thyroidectomy

Treatment and study plan

Thyroidectomy and parathyroid reimplantation in forearm subcutaneous tissue

Procedure

Primary outcomes

Assessment of parathyroid tissue graft function by selective (left or right) parathormone measurement by vein blood sample

Time frame: up to 3 months

The primary outcome will be the assessment of reimplanted parathyroid function, evaluated by intact Parathormone (iPTH) measurement by separate blood samples (left and right arm) at 7 days, 1 month and 3 months after surgery. Ratio of 1.5 between the iPTH levels in the arm receiving graft and the opposite arm will be predictive of graft functionality

Sponsors and collaborators

Lead sponsor

University of Roma La Sapienza

Other

Registry information

Official study title

Arathyroid Reimplantation in Forearm Subcutaneous Tissue During Thyroidectomy: a Simple Way to Avoid Ipoparathyroidism and Evaluate Graft Function

Important dates

Study start: 2014
Primary completion: 2014
Study completion: 2014
First posted: Jul 18, 2014
Registry last updated: Nov 5, 2014

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed