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OpenTrials
Completed

NCT Number: NCT03269851

Parameters of Neurological Deficit After Thoracolumbar Fractures

To detect Radiological parameters affecting neurological injury after thoracolumbar spinal fractures.

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Key information

Conditions

Spinal Fracture Back Injuries Fractures, Bone Nervous System Diseases Neurologic Manifestations Pathological Conditions, Signs and Symptoms Signs and Symptoms Spinal Fractures Spinal Injuries Wounds and Injuries

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Assiut University Hospital

Asyut, Egypt

About this study

Thoracolumbar spine fractures are the most common spinal column fractures. High activity and lack of stability make it more prone to fractures.

Many studies have attempted to determine whether the neurological deficit in such fractures is related to spinal canal stenosis or other parameters observed on axial computed tomography (CT). However, this relationship remains controversial.

Few reports shed light on the relation between different imaging parameters like sagittal alignment, vertebral body compression, canal stenosis, and type of fracture according to AO classification with the severity of nerve damage.

These four radiographic parameters will be tested as expected risk factors for the neurological deficit in thoracolumbar fractures.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Any patient with Acute (within one month) thoracolumbar spine fracture above 18 years old with or without neurological deficit
  • In orthopaedics and trauma department of Assiut university hospital from 1st of November 2018 to 31 st of October 2019.

Exclusion criteria

  • Patients younger than 18 years old.
  • Patients suffering from preoperative neurological diseases that hinder our examination like peripheral neuropathy or previous strokes.
  • Obtuned patients who cannot be properly examined like those with low GCS score.
  • Patients with old thoracolumbar fractures more than one month duration.
  • Patients with pathological spine fractures like those with osteoporosis and cancer metastasis.
  • Patients with fracture type A0 according to AO classification.

Treatment and study plan

computed tomography

Radiation

ct will be done to detect radiological risk factors for neurological deficits after thoracolumbar fractures

Primary outcomes

  1. To Measure spinal canal stenosis by cubic cm

    Time frame: one year

    CT-Radiological parameters measured in patients with or without thoracolumbar fractures .

  2. To measure sagittal alignment of vertebral column by cobb angle

    Time frame: one year

    CT-Radiological parameters measured in patients with or without thoracolumbar fractures

  3. To measure vertebral body compression by cm

    Time frame: one year

    CT-Radiological parameters measured in patients with or without thoracolumbar fractures

  4. To measure type of fracture according to AO classification

    Time frame: one year

    CT-Radiological parameters measured in patients with or without thoracolumbar fractures

Secondary outcomes

  1. Proportion of Neurological deficit among patients with thoracolumbar spine fractures.

    Time frame: one year

    Number of patients with neurological deficit to the total number of patients with thoracolumbar spine fractures.

Sponsors and collaborators

Lead sponsor

Assiut University

Other

Registry information

Official study title

Radiological Parameters Predicting Neurological Injury After Thoracolumbar Spinal Fractures

Important dates

Study start
2018
Primary completion
2019
Study completion
2020
First posted
Sep 1, 2017
Registry last updated
Jul 26, 2021

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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