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Completed

NCT Number: NCT06608290

Paraesternal Blockade and Lactate Serum Levels in Patients With Cardiac Surgery.

Parasternal blockade has been related to a reduction of the postoperative inflammatory response, by inhibition of the stress response, leading to a better prognosis. Increased lactate level is a useful parameter in identifying patients at risk of postoperative morbidity and mortality. The objective was to evaluate the association between parasternal blockade and serum lactate level in patients undergoing cardiac surgery, both trans- and post-anesthesia. 86 patients between 60-70 years of age participated. An association was found between the application of parasternal blockade in cardiac surgery and the presence of lower trans and postanesthetic serum lactate levels.

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Key information

Conditions

Parasternal Block Cardiac Surgery Serum Lactate

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 3

Primary location

Unidad de Investigación Biomédica 02, Unidad Médica de alta especialidad, Hospital de Especialidades Centro Médico Nacional de Occidente, Instituto Mexicano del Seguro Social, Guadalajara 44329, México

Guadalajara, Jalisco, 44329, Mexico

About this study

An analytical cross-sectional study in adult patients who underwent elective cardiac surgery. A total sample of 86 patients was obtained, 43 in the case group and 43 in the control group. Adult patients older than 18 years, of either sex, with ASA II-III, patients who underwent cardiac surgery with median sternotomy and use of cardiopulmonary bypass were included.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Adult patients over 18 years of age
  • Either sex
  • ASA II-IV
  • Patients who underwent cardiac surgery with median sternotomy and use of cardiopulmonary bypass.

Elimination criteria

  • Patients with pre-existing conditions that could independently affect serum lactate levels

Treatment and study plan

parasternal block

Procedure

Administration of parasternal block with ropivacaine, bilaterally at the sternum before the start of surgery.

Lactate serum level

Diagnostic Test

Blood samples were taken to identify serum lactate levels greater than 2 mmol/l and those that remained below this limit.

Primary outcomes

  1. Lactate serum levels

    Time frame: 24 Hours

    Blood samples were taken to identify serum lactate levels greater than 2 mmol/l and those that remained below this limit.

Sponsors and collaborators

Lead sponsor

Instituto Mexicano del Seguro Social

Other Gov

Registry information

Official study title

Association Between the Application of Parasternal Blockade and Serum Lactate Level in Trans and Post-anesthetic Stages in Cardiac Surgery.

Important dates

Study start
2022
Primary completion
2022
Study completion
2024
First posted
Sep 23, 2024
Registry last updated
Sep 24, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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