Pain of Premature Babies and RetCam (DOLICAM)

It is a single-center prospective observational descriptive study.

The studied children will be premature infants hospitalized in the neonatology department of the University Hospital of Grenoble and for whom the RetCam examination is planned for screening for retinopathy of prematurity if they are at risk (prematurity <32 weeks). These exams fit into a routine care.

To measure their pain during the examination, it will be a matter of filming the face of the child for 15 seconds before the examination, then 2 times 30 seconds at two distinct times.

The PIPP (Premature Infant Pain Profile) score includes a percentage of time on these 30 seconds where 3 items are found modified and a monitoring of heart rate and oxygen saturation. (Please note that the recording of the constants of the child is already integrated into the current care in the neonatology department of the University Hospital of Grenoble and will not be added for the purpose of the study.) Expected scores should be about 12/21, despite the use of analgesic agent.

This time calculation can not be done live and requires video recording of the child's face during the exam. After parental information and non-opposition consent of the parents, the child can be filmed and his constants annotated during the current care. Parents can attend this observational procedure.

The statistical analyzes will be adjusted for sex, gestational age at birth, weight, and pain from birth (determined by the number of doses of level 1 analgesics received by the baby and the number of days (from birth to to the RetCam examination) when the baby received > level 1 analgesics).

Inclusion criteria

• Premature born before 31 weeks of Gestational Age or birth weight less than 1250 grams or less than 1300 grams and less than 33 weeks of Gestational age, with risk factor (prolonged oxygen therapy, sepsis, prolonged use of inotropes)
• Corrected age above 31 weeks of gestational age at the time of inclusion
• Having to do a RetCam exam in the neonatology department of the University Hospital of Grenoble.
• No opposition of the subject's parents

Exclusion criteria

• Subject under guardianship or subject deprived of liberty
• Premature requiring a respiratory aid limiting the observation of the face at the time of the examination.
• Non-compliance with the analgesic protocol of the service, prior to examination (paracetamol and sugar solutions).
• Prematurity with a facial malformation and / or neurological disorder that prevents the rating of pain by the PIPP scale