P300 Brain Computer Interface Keyboard to Operate Assistive Technology

The purpose of this research is to develop tools enable people who are paralyzed to operate technology and access computers. These tools are called brain computer interfaces (BCIs). BCIs would let a person use brain signals to operate technology.

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Key information

Conditions

Healthy Amyotrophic Lateral Sclerosis Brain Damage, Chronic Brain Diseases Central Nervous System Diseases Cerebral Palsy Metabolic Diseases Motor Neuron Disease Nervous System Diseases Neurodegenerative Diseases Neuromuscular Disease Neuromuscular Diseases Nutritional and Metabolic Diseases Proteostasis Deficiencies Spinal Cord Diseases Spinal Cord Injuries Spinal Cord Injury TDP-43 Proteinopathies Trauma, Nervous System Wounds and Injuries

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 1 / Phase 2

Primary location

University of Michigan Direct Brain Interface Project, Ann Arbor, Michigan, United States

About this study

The purpose of this research is to develop tools to help people who are paralyzed. These tools are called brain computer interfaces (BCIs). BCIs would let a person use brain signals to operate technology. The investigators want to make a BCI that can be used to operate commercially available technologies for communication, environmental control or computer access. The BCI would replace a keyboard to let people operate these technologies without moving. However, the investigators need people to test the BCI so that the investigators can see how well it can replace a keyboard. The investigators want to understand how well it can work so that the investigators can make it useful for people who are paralyzed. The investigators will ask people to use the BCI to do things like make a communication system speak or type words on a computer.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Age 18 or older.
Able to read text on a computer screen
Able to understand and remember instructions concerning participation

Exclusion criteria

Unable give informed consent.
Unable to understand and follow instructions.
Have abnormal tone or uncontrolled movements in the head-and-neck that would interfere with EEG recordings.
Known to have photosensitive epilepsy.
Open head lesions or sores

Treatment and study plan

Brain Computer Interface Keyboard

Device

Subjects will wear an EEG cap for 1-4 hours (1-2 hours typical) per session and use the brain-computer interface to operate assistive technology. Subjects will be asked to participate in 3 sessions.

Primary outcomes

Accuracy of Typing With BCI Keyboard.

Time frame: mean score from 3 sessions over 29 days

Accuracy for the sentence typed in each environment was calculated as the percentage of characters for which the result character matched the target character. The target characters were determined based on the next character needed to complete the sentence to be copied. In the case of errors, the next character was therefore a backspace to correct the error. The target characters were modified by subject comments to account for errors in selecting the next character.

Once sentence was typed in each environment in each session on a separate day. From the three repeated sessions, there were therefore 9 total sentences per subject with 3 measures for each environment. These were treated as repeated measures for the analysis.

Sponsors and collaborators

Lead sponsor

University of Michigan

Other

Collaborators

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
U.S. Department of Education

Registry information

Important dates

Study start: 2008
Primary completion: 2012
Study completion: 2012
First posted: Mar 13, 2009
Registry last updated: Jul 9, 2015

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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Completed