Barts Health NHS Trust Dental Hospital
London, E1 1BB, United Kingdom
NCT Number: NCT04971174
The aim of this recall study is to evaluate outcomes of surgical regenerative treatment of periodontal defects in a cohort of patient previously treated for gum disease at the Royal London Hospital as part of their periodontal care.
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Notify Me18 year and older
All sexes
Observational
London, E1 1BB, United Kingdom
This study will be divided in two parts:
Part 1: a retrospective analysis of short-term outcomes of periodontal regenerative procedures undertaken at the Barts Royal London Dental Hospital (RLDH); Part 2: a single recall visit study in which patients identified through part 1 and willing to consent for the study will be reassessed for medium-term outcomes of the regenerative procedures previously undertaken.
For part 1 historic data will be collected from available dental records at RLDH and divided in:
For part 2 data will be collected from patients identified through part 1 and willing to give consent for a single study recall visit:
•Timepoint 2: single study outcome recall visit (full mouth periodontal assessment and x-ray of same site/s at Timepoint 0).
Due to the nature of the study, the time elapsed between Timepoint 0 and Timepoint 2 can vary between 1 and 4 years.
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Inclusion criteria
for part 1 of the study:
Additional inclusion criteria for part 2:
-Patient able and willing to give informed consent
Exclusion criteria
Exclusion criteria
for part 1:
Exclusion criteria
for part 2:
Time frame: Through study completion, an average of 2 years
Pocket closure is defined as PPD < and = 4 mm with no bleeding on probing (BoP)
Time frame: Measured at Timepoint 1 (from 6 months up to 1 year)
Secondary outcome
Time frame: Changes measured from baseline (Timepoint 0) to Timepoint 1( from 6 months up to 1 year) and Timepoint 2 (through study completion, an average of 2 years)
Secondary outcome
Time frame: Changes measured from baseline (Timepoint 0) to Timepoint 1( from 6 months up to 1 year) and Timepoint 2 (through study completion, an average of 2 years)
Secondary outcome
Time frame: Changes measured from baseline (Timepoint 0) to Timepoint 1( from 6 months up to 1 year) and Timepoint 2 (through study completion, an average of 2 years)
Secondary outcome
Time frame: Changes measured from baseline (Timepoint 0) to Timepoint 1( from 6 months up to 1 year) and Timepoint 2 (through study completion, an average of 2 years)
Secondary outcome
Time frame: Changes measured from baseline (Timepoint 0) to Timepoint 1( from 6 months up to 1 year) and Timepoint 2 (through study completion, an average of 2 years)
Secondary outcome
Time frame: Changes measured from baseline (Timepoint 0) to Timepoint 1( from 6 months up to 1 year) and Timepoint 2 (through study completion, an average of 2 years)
Secondary outcome
Time frame: Changes measured from baseline (Timepoint 0) to Timepoint 1( from 6 months up to 1 year) and Timepoint 2 (through study completion, an average of 2 years)
Secondary outcome
Time frame: Changes measured from baseline (Timepoint 0) to Timepoint 1( from 6 months up to 1 year) and Timepoint 2 (through study completion, an average of 2 years)
Secondary outcome
Time frame: Assessed at Timepoint 1 ( from 6 months up to 1 year) and Timepoint 2 (through study completion, an average of 2 years)
Secondary outcome- Measured as % of sites with pocket closure (PPD< and = 4mm with no BoP)
Time frame: Assessed at Timepoint 1 ( from 6 months up to 1 year) and Timepoint 2 (through study completion, an average of 2 years)
Secondary outcome- Measured as % of sites with pocket closure (PPD< and = 4mm with no BoP)
Time frame: Assessed at Timepoint 1 ( from 6 months up to 1 year) and Timepoint 2 (through study completion, an average of 2 years)
Secondary outcome- Measured as % of sites with pocket closure (PPD< and = 4mm with no BoP)
Time frame: Assessed at Timepoint 1 ( from 6 months up to 1 year) and Timepoint 2 (through study completion, an average of 2 years)
Secondary outcome- Measured as % of sites with pocket closure (PPD< and = 4mm with no BoP)
Time frame: Assessed at Timepoint 1 ( from 6 months up to 1 year) and Timepoint 2 (through study completion, an average of 2 years)
Secondary outcome- Measured as % of sites with pocket closure (PPD< and = 4mm with no BoP)
Time frame: Assessed at Timepoint 1 ( from 6 months up to 1 year) and Timepoint 2 (through study completion, an average of 2 years)
Secondary outcome- Measured as % of sites with pocket closure (PPD< and = 4mm with no BoP)
Queen Mary University of London
Other
Short & Medium Term Outcomes of Periodontal Regenerative Procedures. A Two-part Study With a) Analysis of Periodontal Records of a Cohort of Periodontitis Patients and b) a Single Visit Recall and Comprehensive Periodontal Re-evaluation
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View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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