Effectiveness of Hyaluronic Acid (hyaDENT BG® Gel) Compared With Enamel Matrix Proteins (Emdogain®) in the Treatment of Angular Bone Defects in Combination With a Xenograft (Bio-Oss Collagen®)

Inclusion criteria

• Adults over the age of 18 diagnosed with periodontal disease-Stage III or IV periodontitis;

• Sites with bone defects and a probing pocket depth (PPD) ≥ 6 mm, accompa-nied by bleeding on probing (BoP) at re-evaluation, conducted six weeks after non-surgical periodontal therapy;
• Full Mouth Plaque Score (FMPS) < 20% and Full Mouth Bleeding Score (FMBS) < 15% prior to surgical treatment;
• Good general health with no systemic conditions and no known allergies to materials or medications used in the study.

Exclusion criteria

• Medical conditions contraindicating surgical intervention;

• Pregnancy or lactation;
• Heavy smokers;
• Untreated periodontal disease;
• Poor oral hygiene;
• Acute infectious lesions in the area of intervention;