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NCT Number: NCT07604493

Oral Health and Systemic Diseases: Survey of General Practitioners

This cross-sectional observational study aims to assess the level of knowledge, clinical practices, and professional attitudes of General Practitioners (GPs) regarding oral health and its relationship with major systemic diseases, with particular emphasis on periodontal disease. Data will be collected through an anonymous, self-administered digital questionnaire distributed nationwide to General Practitioners practicing in Italy. The questionnaire will investigate participants' knowledge of oral diseases, awareness of oral-systemic associations, early identification of oral manifestations, educational background, and interdisciplinary collaboration with dental professionals.

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Sapienza università di Roma

Roma, RM, 00161, Italy

Location status: Recruiting

Location contact

Fabrizio Guerra

CONTACT

[email protected]

3283150627

About this study

The aim of this study is to conduct an exploratory survey designed to assess the level of knowledge among General Practitioners (GPs) regarding the main diseases of the oral cavity, particularly dental caries and periodontal diseases, and their associations with systemic conditions, with special attention to autoimmune, dysmetabolic, and cardiovascular diseases.

To achieve this objective, an anonymous questionnaire consisting of 35 questions has been developed, with an estimated completion time of approximately 10-15 minutes. The questionnaire is intended to investigate participants' familiarity with terminology related to periodontal disease, particularly the terms "periodontitis" and "pyorrhea," which are used to describe the same clinical condition, as well as their level of knowledge regarding its manifestations and clinical implications.

The survey will further investigate General Practitioners' ability to recognize oral signs and symptoms potentially associated with local or systemic diseases, as well as the frequency with which these aspects are considered in routine clinical practice and patient assessment. Information will also be collected regarding previous education and training in oral health-related fields and knowledge of major risk factors associated with oral diseases, including smoking, diabetes mellitus, and medications with significant oral health impact.

Analysis of the collected data will provide insight into the extent to which oral health is integrated into general medical practice, highlighting potential educational gaps and challenges in the early recognition of oral alterations. In addition, the study will assess participants' interest in specific educational and continuing professional development initiatives.

The expected findings may contribute to strengthening collaboration between general medicine and dentistry by promoting shared approaches to prevention, screening, and education aimed at achieving a more comprehensive and integrated management of patients, particularly vulnerable populations. Furthermore, the information obtained may provide useful support for the development of preventive strategies and clinical protocols aimed at improving multidisciplinary patient care.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Licensed General Practitioners currently practicing in Italy
  • Ability to understand and complete the questionnaire in Italian
  • Voluntary agreement to participate after reading study information and providing informed consent

Exclusion criteria

  • Physicians not currently practicing as General Practitioners
  • Incomplete questionnaire responses
  • Duplicate submissions
  • Participants who decline informed consent

Treatment and study plan

questionnaire survey

Other

Participants will complete a questionnaire consisting of 35 closed-ended questions designed to assess General Practitioners' knowledge, clinical practices, and attitudes regarding oral health and its relationship with systemic diseases.

Primary outcomes

  1. General Practitioners' level of knowledge regarding oral diseases and oral-systemic associations

    Time frame: At questionnaire completion (at baseline)

    Knowledge level will be assessed through a predefined set of questionnaire items investigating participants' understanding of:

    • Common oral diseases
    • Periodontal disease
    • Associations between oral and systemic diseases
    • Risk factors and preventive measures The total knowledge score will be calculated by summing the number of correct responses provided by each participant.

    Higher total scores will indicate a greater level of knowledge among General Practitioners regarding oral diseases, periodontal disease, oral-systemic associations, risk factors, and oral health-related clinical practices.

    Scores may additionally be categorized for descriptive analysis as:

    • Low level of knowledge: <50% correct responses
    • Moderate level of knowledge: 50-75% correct responses
    • High level of knowledge: >75% correct responses

Study contacts

Contact information is provided by the study sponsor or research team.

Fabrizio Guerra

CONTACT

[email protected]

3283150627

Sponsors and collaborators

Lead sponsor

University of Roma La Sapienza

Other

Registry information

Official study title

Oral Health and Systemic Diseases: An Investigative Survey of General Practitioners

Important dates

Study start
2026
Primary completion
2026
Study completion
2027
First posted
May 22, 2026
Registry last updated
May 28, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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