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OpenTrials
Completed

NCT Number: NCT06007378

Optimizing Postoperative Pain Control After Laparoscopic Colorectal Surgery

Erector spinae plane block (ESPB) is a novel regional block technique that was proven to have superior outcomes in relieving postoperative pain in colorectal surgeries.Ketamine enhances the impact of local anaesthetics by reducing the duration and extent of motor block while shortening the onset of sensory and motor block.Transdermal Fentanyl Patch (TFP) was better than transdermal buprenorphine in postoperative analgesia following abdominal surgeries.

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Key information

Conditions

Postoperative Pain Neurologic Manifestations Pain Pain, Postoperative Pathologic Processes Pathological Conditions, Signs and Symptoms Postoperative Complications Signs and Symptoms

Age range

21 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Ain-Shams University Hospitals

Cairo, Egypt

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients undergoing laparoscopic colorectal surgery.
  • American Society of Anesthesiologists (ASA) physical status I or II.

Exclusion criteria

  • Known allergy to one of the study medications.
  • Skin infections at the site of the needle puncture.
  • Hepatic, renal or cardiac dysfunction.
  • Patients diagnosed with obstructive sleep apnoea

Treatment and study plan

Bupivacaine and ketamine

Other

Bilateral erector spinae plane block (bupivacaine and ketamine)

Bupivacaine and transdermal fentanyl patch

Other

Bilateral erector spinae plane block (bupivacaine) and transdermal fentanyl patch

Bupivacain

Other

Bilateral erector spinae plane block (bupivacaine)

Primary outcomes

  1. The time to first rescue analgesia after surgery (hour)

    Time frame: The first 48 hours after surgery

    The time to first rescue analgesia after surgery (hour)

Sponsors and collaborators

Lead sponsor

Ain Shams University

Other

Registry information

Official study title

Optimizing Postoperative Pain Control After Laparoscopic Colorectal Surgery by Supplementing Ultrasound-guided Erector Spinae Plane Block With Ketamine or Transdermal Fentanyl Patch

Important dates

Study start
2023
Primary completion
2025
Study completion
2025
First posted
Aug 23, 2023
Registry last updated
Feb 18, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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