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OpenTrials
Completed

NCT Number: NCT00243360

Optimizing Antibiotic Use in Long Term Care

The purpose of this study was to determine if a multi-faceted intervention to implement diagnostic and therapeutic algorithms for management of suspected urinary infection in nursing home residents could reduce antibiotic prescribing for urinary indications in this population.

Completed

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Key information

Conditions

Urinary Tract Infection, Antibiotic Use Female Urogenital Diseases Female Urogenital Diseases and Pregnancy Complications Infections Male Urogenital Diseases Urinary Tract Infections Urogenital Diseases Urologic Diseases

Age range

0 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

McMaster University

Hamilton, Ontario, L8N 3Z5, Canada

About this study

Antibiotic use is intense in nursing homes and frequently inappropriate when prescribed for urinary indications. Evidence from randomized controlled trials suggests that treatment of asymptomatic bacteriuria, the presence of bacteria in the urine in the absence of urinary symptoms, is not beneficial. Despite this, one in three prescriptions for urinary indications are for asymptomatic bacteriuria. To improve antibiotic prescribing in this setting we conducted a cluster randomized trial of a strategy to implement diagnostic and treatment algorithms for urinary infection. 24 nursing homes were randomized to either the intervention (implemented at the nursing home level using a multi-faceted approach: small group interactive sessions for nurses, one-on-one interviews for physicians, videotapes, written material, and outreach visits) or to usual care.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Individuals- all residents eligible
  • Nursing homes
  • Free standing long term care facilities with >100 beds
  • No stated policy for diagnosis or treatment of urinary tract infections
  • The facility agrees to refrain from introducing new strategies for antibiotic utilization or clinical pathways during study

Exclusion criteria

-

Treatment and study plan

diagnostic and treatment clinical algorithms

Behavioral

Primary outcomes

  1. Antimicrobial prescriptions

Secondary outcomes

  1. Urinary cultures,

  2. hospitalizations, deaths

Sponsors and collaborators

Lead sponsor

Agency for Healthcare Research and Quality (AHRQ)

Fed

Registry information

Important dates

Study start
2001
Study completion
2003
First posted
Oct 24, 2005
Registry last updated
Oct 24, 2005

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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