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NCT07566403
Arterial Occlusive Diseases, Arteriosclerosis
Bergamo, Italy
View Trial DetailsNCT Number: NCT06886893
This study aims to evaluate how optical coherence tomography (OCT) can help predict outcomes in patients with retinal vein occlusion (RVO), a condition that affects blood flow in the retina. RVO can cause macular edema, which is swelling in the part of the eye responsible for central vision. The study will use OCT scans to assess changes in the retina and how these changes relate to vision improvement over time.
Trial opening soon.
Get Notified18 year and older
All sexes
Observational
Objectives Evaluate how OCT data can predict visual outcomes by analyzing retinal changes and macular edema characteristics.
Assess the correlation between baseline OCT biomarkers and visual acuity improvements over time.
Study Design Type: Cross-sectional study.
Setting: Conducted at several eye care centers in Egypt.
Participants Inclusion Criteria: Adults with branch or central RVO, macular edema confirmed by OCT, and no prior RVO in the affected eye.
Exclusion criteria
Other retinal diseases, recent intraocular surgery, or significant media opacities.
Procedures Informed Consent and History Taking.
Ophthalmologic Examination: Includes BCVA, IOP, slit-lamp biomicroscopy, and fundus examination.
OCT Imaging: Using NIDEK RS-330 Retina scan duo 2 (SD-OCT) to assess macular changes.
OCT Image Evaluation: Classification of macular edema types and assessment of biomarkers like subretinal fluid and cystoid changes.
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Patients diagnosed with branch or central retinal vein occlusion.
Patients with macular edema confirmed by OCT due to vein occlusion.
Patients with no prior history of RVO in the affected eye.
Exclusion criteria
History of intraocular surgery within the last three months.
Presence of significant media opacities (e.g., dense cataract, vitreous hemorrhage) that interfere with OCT imaging.
Time frame: 6 months
Correlation between baseline OCT biomarkers and visual acuity at presentation after 1, 3, and 6 months post-treatment.
Assiut University
Other
Optical Coherence Tomography Data As a Prognostic Indicator in Retinal Vein Occlusion
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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