Optical Biopsy of Human Skin in Conjunction With Laser Treatment

This study is to compare the ability of optical biopsy. Research can use light enters the skin, collected, analyzed by the computer, and a picture created for the pathologist to conventional histologic examination compare with the pathologist looking at the piece of tissue through a microscope makes the diagnosis.

Completed

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Key information

Conditions

Malignant Melanoma Adenocarcinoma Atypical Nevi Basal Cell Carcinoma Bone Diseases Burns Carcinoma Carcinoma, Basal Cell Carcinoma, Merkel Cell Carcinoma, Neuroendocrine Carcinoma, Squamous Cell Congenital Abnormalities Congenital Nevi Congenital, Hereditary, and Neonatal Diseases and Abnormalities Connective Tissue Diseases DNA Virus Infections Dermatofibroma Dysplastic Nevus Syndrome Genetic Diseases, Inborn Hemangioma Herpesviridae Infections Histiocytoma Histiocytoma, Benign Fibrous Infections Kaposi's Sarcoma Keratosis Keratosis, Seborrheic Melanoma Merkel Cell Carcinoma Musculoskeletal Diseases Neoplasms Neoplasms by Histologic Type Neoplasms by Site Neoplasms, Basal Cell Neoplasms, Connective Tissue Neoplasms, Connective and Soft Tissue Neoplasms, Fibrous Tissue Neoplasms, Germ Cell and Embryonal Neoplasms, Glandular and Epithelial Neoplasms, Nerve Tissue Neoplasms, Squamous Cell Neoplasms, Vascular Tissue Neoplastic Syndromes, Hereditary Neuroectodermal Tumors Neuroendocrine Tumors Nevi and Melanomas Nevus Osteitis Deformans Paget's Disease Polyomavirus Infections Port Wine Stain Port-Wine Stain Sarcoma Sarcoma, Kaposi Scleroderma Scleroderma, Diffuse Scleroderma, Systemic Seborrheic Keratosis Skin Abnormalities Skin Diseases Skin Neoplasms Skin and Connective Tissue Diseases Squamous Cell Carcinoma Tattoos Tumor Virus Infections Virus Diseases Wounds and Injuries

Age range

18 year–75 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Beckman Laser Institute, Unversity of California Irvine

Irvine, California, 92612, United States

About this study

The Optical measurements provide quantitative optical property values that reflect changes in tissue perfusion, oxygen consumption, and cell/matrix development. Each measurement requires less than 5 minutes to execute. The measurements will be taken before and after skin treatment.This non-invasive, non-contact technique has great potential as a means to diagnose different skin problems without the need to obtain a piece of tissue from the skin.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Male or female age > 18 years

Exclusion criteria

current participation in any other investigational drug evaluation
inability to understand and carry out instructions

Treatment and study plan

Optical Biopsy imaging

Device

Optical Biopsy imaging

Primary outcomes

normal skin

Time frame: 12 weeks

Sponsors and collaborators

Lead sponsor

University of California, Irvine

Other

Collaborators

Beckman Laser Institute University of California Irvine

Registry information

Important dates

Study start: 1999
Primary completion: 2008
Study completion: 2008
First posted: Oct 8, 2007
Registry last updated: Oct 20, 2022

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed