Opioid-Free Orthopaedic Surgery

Inclusion criteria

• Patient is scheduled to undergo one of the following procedures:

• Primary single-level or two-level ACDF or ACDA for degenerative disease
• Primary 1st CMC arthroplasty
• Primary Hallux Valgus or Hallux Rigidus correction
• Diagnostic knee arthroscopy +/- meniscal debridement
• Elective primary total shoulder or reverse total shoulder arthroplasty
• Primary total hip arthroplasty

Exclusion criteria

• Revision surgery for one of the study-specific procedures
• Chronic opioid therapy - per investigator discretion
• Significant liver disease - (NOTE: Patients with a history of liver disease will have a hepatic panel drawn to be reviewed by the study investigator to asses if the values are within acceptable limits for inclusion in the study)
• Fracture or soft tissue injury
• Sickle cell disease
• Workers compensation
• Alcohol dependence
• Contra-indication to regional anesthesia
• History of gastrointestinal (GI) bleeding or peptic ulcer
• History of bleeding problems
• Patients taking anticoagulants, not including aspirin (only applies to Randomized portion of study. These patients can still participate in Observational Control Group)
• Renal insufficiency - Creatinine clearance less than 30 mL/min (only applies to patients having surgery requiring NSAIDs treatment)
• Outpatient THA or TSA/RTSA
• Hammertoe in isolation (Hallux Valgus/Rigidus exclusion only)
• Concomitant meniscal repair or microfracture (Knee Arthroscopy exclusion only)
• Ineligible for spinal anesthesia (THA exclusion only)
• Previous ipsilateral hip surgery, not including hip scope (THA exclusion only)
• Allergy to non-steroidal anti-inflammatory medications (NSAIDs)