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OpenTrials
Completed

NCT Number: NCT07386301

Open Membrane Technique as an Innovative Minimally Invasive Technique for Bone Augmentation

Sixteen patients with horizontal deficiencies in the posterior mandible were treated with "the Open Membrane Technique" (OMT). Dense PTFE membranes covering an allograft biomaterial were used without any attempt to passivate the flap. Flap closure with an open wound (membrane exposure) was monitored weekly for up to 6w at the time of membrane removal. At implant placement, soft and hard tissue gains were assessed clinically and radiographically. Bone cores were harvested for histological analysis from the implant preparation sites

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Key information

Conditions

Bone Graft Keratinized Tissue

Age range

17 year–70 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Clinic 506

Beirut, Lebanon

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Healthy adults Free of any systemic disease affecting bone metabolism Highly compliant Good oral hygiene Willing to sign informed consents prior to their inclusion

Exclusion criteria

Untreated periodontal disease Heavy smokers Excessive alcohol consumption Uncontrolled systemic conditions

Treatment and study plan

Bone Augmentation

Procedure

Dense PTFE membranes covering an allograft biomaterial were used without any attempt to passivate the flap

Primary outcomes

  1. Hard tissue gain

    Time frame: 5 months

    Bone thickness measured clinically and on CBCT (during bone grafting and at re-entry)

Secondary outcomes

  1. Soft Tissue Gain

    Time frame: 5 months

    Keratinized tissue measured clinically before and after the treatment (at implant placement)

Sponsors and collaborators

Lead sponsor

Saint-Joseph University

Other

Registry information

Official study title

Open Membrane Technique as an Innovative Minimally Invasive Technique for Hard and Soft Tissue Augmentation: a Retrospective Case Series

Important dates

Study start
2019
Primary completion
2025
Study completion
2025
First posted
Feb 4, 2026
Registry last updated
Feb 4, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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