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NCT Number: NCT07575074

OKT With Gaze and Postural Stabilization on Vertigo, MS and QOL in VBH

The objective of this study will evaluate the effects of optokinetic training combined with postural stabilization and gaze stability exercises on motion sickness, balance, gaze stability, and quality of life in individuals with vestibular hypofunction.

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Key information

Conditions

Vestibular Disorder Ear Diseases Labyrinth Diseases Motion Sickness Otorhinolaryngologic Diseases Pathological Conditions, Signs and Symptoms Signs and Symptoms Vestibular Diseases

Age range

20 year–40 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Ittefaq Hospital Lahore

Lahore, Punjab Province, 54500, Pakistan

Location contact

Asad Shahzad Mir, MsNMPT

PRINCIPAL_INVESTIGATOR

Javeria Ghazal, MSNMPT

CONTACT

[email protected]

+923335154664

About this study

A randomized clinical trial will be conducted with 32 participants assigned to two groups: Group A (breathing and aerobic exercises) and Group B (optokinetic training combined with postural stabilization and gaze stability exercises). Data will be collected using the Motion Sickness Susceptibility Questionnaire (MSSQ), Berg Balance Scale (BBS), Dynamic Visual Acuity Test for Gaze Stability, and Head Impulse Test. Statistical analysis will be performed by SPSS.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • • Male and female patients age 20 and 40 years
  • Passengers who have motion sickness during travelling
  • Patients of vestibular migraine who experience motion sickness
  • Participants experiencing vertigo, dizziness or imbalance related to vestibular hypofunction over the past three months

Exclusion criteria

  • • Patients who have seasickness and simulator sickness excluded.
  • Patients having vestibular disease and chronic neurological disease.
  • Participants who have completed formal vestibular rehabilitation in last 6 months excluded
  • Patients with severe visual impairments and orthopedic conditions excluded.

Treatment and study plan

Group A Habituation exercises

Other

Habituation exercises five times per week to improve overall wellness and reduce baseline symptoms of motion sickness (38). Each session, lasting approximately 20-25 minutes, involved exercises conducted for 20 minutes per day, five times a week. Each session, lasting approximately 30-45 minutes, included low-intensity breathing exercises aimed at promoting relaxation and moderate-intensity aerobic activities, such as walking or cycling, at 50-60% of the participant's maximum heart rate.

Group B Optokinetic training protocol

Other

10-minute warm-up, followed by 20-25 minutes of moderate-intensity optokinetic exercises (viewing controlled moving visual patterns), postural exercises involving controlled head and body movements to engage the vestibular system, and gaze stability exercises, which require focusing on a stationary target during head movements to improve the vestibulo-ocular reflex. The session concluded with a 10-15-minute cool-down to aid relaxation. These sessions continued for 12 weeks

Primary outcomes

  1. Motion sickness susceptibility questionnaire

    Time frame: 8th week

    The Motion Sickness Susceptibility Questionnaire (MSSQ) is a widely used tool that assesses an individual's predisposition to motion sickness in various environments, such as vehicles, amusement rides, and virtual reality.

  2. Berg balance scale

    Time frame: 8th week

    The Berg Balance Scale (BBS) is a reliable clinical tool used to assess balance in individuals, particularly older adults and those with balance impairments. It includes 14 tasks each scored from 0 (cannot perform) to 4 (performs independently). The BBS has a maximum score of 56, and most of the patients show a low fall risk of 41 to 56 scores, medium risk of 21 to 40 scores, and a high risk of 0 to 20 scores.

  3. Dynamic visual acuity test for gaze stability

    Time frame: 8th week

    The Dynamic Visual Acuity (DVA) Test is a widely used clinical test to assess gaze stability, particularly in individuals with vestibular dysfunction. It evaluates a person's ability to maintain clear vision during head movements, which requires stable gaze control. The test involves reading porotype letters or symbols displayed on a screen, first in a stationary position and then while moving the head horizontally and vertically at a standardized speed (usually around 2 Hz)

  4. Head impulse test

    Time frame: 8th week

    The Head Impulse Test (HIT) is a diagnostic tool used to evaluate the function of the vestibulo-ocular reflex (VOR), essential for maintaining gaze stability during rapid head movements. In this test, a clinician rapidly and unpredictably turns the patient's head to the left or right while the patient focuses on a stationary target, typically the clinician's nose. For a healthy VOR, the eyes should remain fixed on the target despite the head movement

Study contacts

Contact information is provided by the study sponsor or research team.

Muneeb Khan, PhD

CONTACT

[email protected]

923367993611

Sponsors and collaborators

Lead sponsor

Riphah International University

Other

Registry information

Official study title

Effects of Optokinetic Training With Gaze and Postural Stabilization on Vertigo, Motion Sickness and Quality of Life in Vestibular Hypofunction

Important dates

Study start
2026
Primary completion
2026
Study completion
2026
First posted
May 8, 2026
Registry last updated
May 8, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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