Skip to main content
OpenTrials
Completed

NCT Number: NCT05287269

Ocular Coherence Tomography During Cataract Assessment

Many patients will have underlying maculopathy present when undergoing cataract surgery, which are not visible on fundoscopy alone. Knowledge of this underlying pathology will allow an improved consenting process and discussion with the patient regarding the risks, visual prognosis and recovery following cataract surgery. Incidental findings in the fellow eye would also allow for improved diagnosis and management of these patients without adding significant additional time to specialist high volume cataract assessment clinics.

Completed

Looking for future studies?

Notify Me

Key information

Age range

Up to 100 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Brighton & Sussex University Hospitals NHS Trust

Brighton, Sussex, BN2 5BF, United Kingdom

About this study

The majority of anterior segment pathology may be diagnosed with simple slit lamp biomicroscopy, but posterior segment pathology may not be quite so obvious and can be missed on simple examination especially if a visually significant cataract is present impeding the view. There is also a degree of subjectivity from how much the cataract impairs the vision in comparison to the other elements of the optical pathway within the eye, and whilst there is no single way to evaluate this.

Optical coherence tomography (OCT) has been widely present in ophthalmology clinics since it's development 20 years ago although it is not commonly used in all units for the pre-operative assessment of patients referred for cataract surgery in high volume set ups such as the National Health Service (NHS) in the United Kingdom. There may still be reluctance to use OCT in a normal cataract assessment clinic as it may be perceived as an additional step that decreases time efficiency and increase financial investment in the services.

In this study we sought to investigate the prevalence of retinal pathology in the patient cohort, the comparison of subjective clinical slit lamp fundoscopy assessmenet with OCT findings and the co-incidental OCT findings in the fellow eye at the time of cataract assessment. OCT was chosen as the most efficient way to support clinicians in the assessment clinics, and to see if the addition of this step added value to the patient consultation and pre-operative assessment.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients referred for cataract surgery

Exclusion criteria

  • Patients unable to attend the cataract assessment clinic
  • Morbid patients who cannot be assessed on OCT or slit lamp

Treatment and study plan

Ocular Coherence Tomography

Diagnostic Test

OCT images were recorded as a fast macular radial line scan with captured on either Heidelberg Spectralis (Heidelberg Engineering GmbH, Germany) or Topcon DRI Triton (Topcon Medical Systems inc. USA).

Other names: Swept Source ocular coherence tomography

Primary outcomes

  1. Incidence of occult macular pathologies in the eye referred for cataract surgery

    Time frame: During the cataract assessment clinic

    Comparison of slitlamp biomicroscopy fundus finding with ocular coherence tomography (OCT) scan of the macula

Secondary outcomes

  1. Incidence of macular pathologies in the fellow eye

    Time frame: During the cataract assessment clinic

    Noting the incidence of macular pathologies noted on OCT

Sponsors and collaborators

Lead sponsor

Brighton and Sussex University Hospitals NHS Trust

Other

Registry information

Official study title

Importance of Ocular Coherence Tomography During Cataract Assessment

Important dates

Study start
2020
Primary completion
2020
Study completion
2020
First posted
Mar 18, 2022
Registry last updated
Nov 3, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.